维生素B12合并洁悠神治疗宫颈癌放射性皮炎的效果研究  

Effect of vitamin B12 with JUC on skin protection in cervical cancer patients with radiation therapy

作　　者：胡水清[1] 缪蔚云[1] 于长华[1] 倪淑玲[1] 潘鹏[1] 

机构地区：[1]江苏省淮安市第一人民医院肿瘤放疗科,223300

出　　处：《中华现代护理杂志》2013年第3期342-344,共3页Chinese Journal of Modern Nursing

摘　　要：目的探讨维生素B12合并洁悠神对宫颈癌患者放射性皮炎的效果。方法将60例宫颈癌放疗发生Ⅱ级以上放射性皮炎患者按信封法随机分为两组，治疗组（30例）采用维生素B12合并洁悠神喷洒破损皮肤，对照组（30例）采用常规皮肤护理，观察两组患者的皮肤损伤修复情况。结果治疗组患者皮肤修复较对照组明显好转，保持放射治疗无中断。总有效率、降级率、稳定率分别为100％，83．3％，16．7％，而对照组分别为73．3％，33．3％，40％，两组比较差异有统计学意义（χ^2=4．00，P〈0．05）。结论洁悠神合并维生素B12对宫颈癌患者放射性皮炎具有良好的治疗效果，且无明显不良反应，使用方便、简单，值得临床推广应用。Objective To explore the effect of vitamin B12 with JUC on skin protection in cervical cancer patients with radiation therapy. Methods A total of 60 patients who had radiodermatitis of degree Ⅱ and above were randomly divided into two groups： the treatment group and the control group, each with 30 patients. Patients in treatment group were treated with vitamin B12 combined with JUC, while patients in control group were treated with routine skin protection measures. Healing of skin damage was observed and compared between two groups. Results Skin repair in treatment group was more obvious than that in control group and radiation therapy was not interrupted. The total effective rate ,degradation rate and stability rate were respectively 100% , 83.3% and 16.7% in treatment group,and 73.3%, 33.3% and 40% in control group, and the differences were statistically significant （ χ^2 = 4.00, P 〈 0.05 ）. Conclusions Vitamin B12 combined with JUC has good effect on radiodermatitis, as well as has advantages of little adverse reaction and convenience, thus is worthy promoting.

关 键 词：宫颈肿瘤 放射性皮炎 维生素B12 护理 洁悠神 

分 类 号：R473.73[医药卫生—护理学]