两种1,3-丙二胺类化合物的合成  

Synthesis of two 1,3-propanediamines

作　　者：陈震[1] 曹晓群[1] 葛燕青[1] 王玉民[1] 

机构地区：[1]泰山医学院化工学院,山东泰安271000

出　　处：《精细与专用化学品》2013年第3期49-50,53,共3页Fine and Specialty Chemicals

基　　金：山东省科技发展计划项目(2011GGH22112)

摘　　要：分别以丙酮和2-丁酮为原料与硝基甲烷在二乙胺催化下反应,得到两种二硝基取代物,然后用甲酸铵催化转移氢化得2,2-二甲基-1,3-丙二胺和2-甲基-2-乙基-1,3-丙二胺。对二硝基取代物和丙二胺的合成分别进行了改进,提高了产率。并对相关反应机理进行了分析。Two compounds of dinitropropane were synthesized from acetone or butanone via reacting with nitromethane in the presence of diethylamine as catalyst. Then they were reduced to 2,2-dimethyl-1,3-propanediamine and 2-eth- yl-2-methy]-1,3-propanediamine by ammonium formate catalytic transfer hydrogenation. Synthetic methods of them were improved and yield of them were increased . Possible mechanism of the reactions were discussed.

关 键 词：1 3-丙二胺 甲酸铵 催化转移氢化 

分 类 号：TQ226.31[化学工程—有机化工]