光学多普勒血液微循环测量技术及其最新进展  

Optical Doppler technologies for micro-circulation measurement and their recent progress

作　　者：尹荣贻[1] 仝雨[2] 赵友全[1] 方晖[2] 

机构地区：[1]天津大学精密仪器与光电子工程学院,天津300072 [2]南开大学现代光学研究所光学信息技术科学教育部重点实验室,天津300071

出　　处：《光学技术》2013年第2期112-123,共12页Optical Technique

基　　金：国家自然科学基金(11074134);教育部新世纪优秀人才支持计划(NCET-10-0502)

摘　　要：血液微循环的测量研究有着非常重要的临床诊断价值。现有的可用于血液微循环测量的光学多普勒技术可分为三大类:激光多普勒技术、相干层析多普勒技术和光声多普勒技术。在介绍这三类技术的基本工作原理和主要特点的基础上,简要分析了各类中最具代表性的前沿技术,分别为激光多普勒宽场实时成像技术、光学相干层析多普勒微血管造影术和光声多普勒流速测量技术。对这些前沿技术的进一步发展和实际应用进行了展望。The measurement and study of micro-circulation own indispensable value in clinical diagnosis. Current op- tical Doppler technologies for micro-circulation measurement can be categorized to three groups, laser Doppler technolo- gies, optical coherence tomography Doppler technologies and photo-acoustic Doppler technologies. Regarding every group, firstly, their basic working principles and major characteristics are introduced, and then the most representative advanced technology is analyzed briefly, namely： full-field real-time laser Doppler imaging, optical coherence tomography Doppler micro-angiography, photo-acoustic Doppler flow measurement. At last, the prospects about the further development as well as practical applications of these advanced technologies are provided.

关 键 词：光学测量 生物光学 血液微循环测量 光学多普勒 激光多普勒 光学相干层析多普勒 光声多普勒 

分 类 号：O436[机械工程—光学工程] R331.35[理学—光学]