脑保护技术在1328例颈动脉狭窄患者支架成形术中的应用  

Clinical application of carotid angioplasty with stenting using cerebral protection technology:report of 1 328 cases

作　　者：李华康[1] 迟路湘[1] 赵刚[2] 刘之荣[2] 向立全[3] 李鱼[3] 田杰[3] 杜彦辉[4] 马斌武[4] 陈桂生[4] 

机构地区：[1]第三军医大学西南医院心血管内科,重庆市介入心脏病学研究所,重庆400038 [2]第四军医大学附属西京医院神经内科,西安710032 [3]重庆市涪陵中心医院神经内科,重庆涪陵408001 [4]宁夏医学院附属医院神经内科,银川750004

出　　处：《第三军医大学学报》2013年第6期562-564,共3页Journal of Third Military Medical University

摘　　要：目的观察脑保护下颈动脉狭窄支架成形术的临床疗效和安全性。方法回顾性分析2003年4月至2010年6月1 328例脑保护下行支架成形术治疗颈动脉狭窄患者的临床资料,分析手术的安全性和有效性。结果 1 328例患者均顺利将脑保护装置于颈动脉入颅处,患者治疗前颈动脉的狭窄率为(88.2±6.7)%,治疗后为(19.2±11.1)%,治疗后颈动脉狭窄明显减轻(P<0.01)。其中768例患者进行了平均1年随访,无1例死亡、缺血性脑卒中发生。结论脑保护下行颈动脉狭窄支架成形术治疗颈动脉狭窄、预防缺血性脑卒中安全、有效。Objective To observe the clinical efficacy and safety of cerebral protection devices and stent angioplasty in the treatment of patients with carotid artery stenosis. Methods The clinical data of 1 328 patients with carotid stenosis treated with cerebral protection devices and stent angioplasty in the departments of cardiology and neurology from 4 different hospitals from April 2003 to June 2010 were analyzed retrospectively. The safety and efficacy of the operation was analyzed. Results Cerebral protection devices were smoothly implanted into the skull of these 1 328 cases through carotid artery. The average carotid artery stenosis rate was decreased from （88. 2 _＋ 6. 7）% before treatment to （19. 2 ±11. 1 ）% after treatment, with significant difference （P 〈0. 01 ）. There were 768 patients who were followed up for average 1 year. During the period, no one case was died, nor ischemic stroke occurred. Conclusion Cerebral protection devices and stent angioplasty is safe and efficient in the treatment of carotid artery stenosis and prevention of ischemic stroke.

关 键 词：颈动脉狭窄 脑保护装置 支架 成形术 

分 类 号：R543.4[医药卫生—心血管疾病] R618[医药卫生—内科学]