Dsl1复合体及其拟南芥同源复合体的最新研究动态  

Latest Update of Dsl1 Complex and Its Arabidopsis Homologous Complex

作　　者：赵潇男[1] 马洪娜[1] 李季[1] 李立新[1] 

机构地区：[1]东北林业大学盐碱地生物资源环境研究中心,东北油田盐碱植被恢复与重建教育部重点实验室,哈尔滨150040

出　　处：《植物生理学报》2013年第2期127-136,共10页Plant Physiology Journal

基　　金：中国博士后科学基金特别资助(200902365);中央高校基本科研业务费专项资金(DL09DA02);国家自然科学基金(30970223)

摘　　要：真核细胞中,各细胞器之间的物质交流是通过膜泡运输完成的。膜泡运输依赖多种跨膜蛋白和可溶性蛋白的协同作用来完成。膜泡运输主要包括运输囊泡的出芽(budding)、定向移动(transport)、拴留(tethering)、锚定(docking)和膜融合(fusion)过程。运输囊泡与靶膜融合的特异性依赖多种保守的跨膜蛋白和可溶性蛋白完成,如衣被蛋白(coat)、拴留蛋白(tether)、SNARE蛋白、SM蛋白和Rab蛋白等。其中,拴留因子负责运输囊泡和靶膜最初的接触。从高尔基体到内质网的逆行性运输过程中起作用的拴留因子是Dsl1复合体及其同源复合体。关于Dsl1复合体的研究目前已经有一定的进展,本文将对Dsl1复合体及其同源物的组成和功能进行介绍。In eukaryotic cells, the communication between various organelles is mediated by vesicle transport. Vesicle transport relies on the cooperation of various transmembrane proteins and soluble proteins. Vesicular transport includes the process of vesicle budding, transport, tethering, docking and fusion. The specificity of transport vesicles fuse to target membrane depends on conserved transmembrane proteins and soluble proteins, such as coats, tethers, SNAREs, SM proteins and Rab proteins. Tethering factors are responsible for the initial contact of transport vesicles with target membrane. Tethering factors which playing the role on retrograde trans- portation from the Golgi apparatus to ER （endoplasmic reticulum） are Dsll complex and its homologous com- plex. There is certain progress on research of Dsll complex. Here we introduce components and function of Dsll complex and its Arabidopsis homologous complex.

关 键 词：膜泡运输 拴留 Dsl1复合体 MAG2复合体 COPI小泡 

分 类 号：Q942[生物学—植物学]