帕瑞昔布钠联合静脉自控镇痛在腔镜甲状腺术后镇痛的临床观察  

Clinical observation of parecoxib sodium combined intravenous patient-controlled analgesia in the postoperative analgesia for laparoscopic thyroidectomy

作　　者：陈灿栋 占海波[1] 段谟舜 

机构地区：[1]广州市花都区人民医院麻醉科,510800

出　　处：《中国实用医刊》2013年第6期43-45,共3页Chinese Journal of Practical Medicine

摘　　要：目的观察帕瑞昔布钠联合静脉自控镇痛（PCA）在腔镜甲状腺术后的镇痛效果。方法将在气管插管全身麻醉下接受腔镜甲状腺大部分切除术的48例患者随机分为两组：观察组26例患者术毕静脉注射帕瑞昔布钠40mg后连接PCA泵，12h后追加帕瑞昔布钠40mg，而对照组22例在术毕仅连接PCA泵。于术后4、8、12和24h时点采用视觉模拟评分法（VAS）进行疼痛评分，同时观测PCA按压次数和用药总量。结果观察组术后4、8、12和24h时点VAS疼痛评分及PCA按压次数和用药总量均明显低于对照组，差异有统计学意义（P〈0．05）。结论帕瑞昔布钠能明显增强腔镜甲状腺术后的镇痛效果，减少PCA的用药量。Objective To observe the effect of parecoxib sodium combined intravenous patient- controlled analgesia（PCA） in the postoperative analgesia for laparoscopic thyroidectomy. Methods Forty- eight patients who underwent laparoscopic thyroidectomy under tracheal intubation general anesthesia randomly divided into two groups, For the observation group 26 patients injected parecoxib sodium 40 mg then connected with PCA pumps after operations, 12 hours after chasing parecoxib sodium 40 mg, while the control group 22 patients just connected with PCA pumps after operations. After 4, 8, 12 and 24 hour time points using VAS pain scores, while observing the PCA pressing times and medication total. Results Observation group after 4,8, 12 and 24 hour time point VAS pain scores and PCA pressing times and medication total were significantly lower than that of control group, the difference was statistically significant （P 〈 0. 05 ）. Conclusions Parecoxib sodium can significantly enhance the analgesic effect of endoscopic thyroid surgery, and reduce the dosage of the PCA.

关 键 词：帕瑞昔布钠 术后镇痛 效果 腔镜 甲状腺切除术 

分 类 号：R614[医药卫生—麻醉学]