盐酸丁丙诺啡用于子宫下段剖宫产术的超前镇痛效果观察  

The preemptive analgesia observation of buprenorphine hydrochloride for the lower uterine segment cesarean section

作　　者：刘晓燕[1] 

机构地区：[1]山西煤炭中心医院,山西太原030006

出　　处：《中国实用医刊》2013年第6期76-77,共2页Chinese Journal of Practical Medicine

摘　　要：目的观察硬膜外腔注入盐酸丁丙诺啡用于子宫下段剖宫产术进行超前镇痛的效果。方法将8ID例ASA I～Ⅱ级择期子宫下段剖宫产术患者于硬一腰联合麻醉后随机分为两组：超前镇痛组（A组）40例，于手术切皮前10min经硬膜外导管注入含盐酸丁丙诺啡0．15mg的生理盐水4ml；对照组（B组）40例，于手术切皮前10min经硬膜外导管注入生理盐水4ml，观察术后4、8、12、24邯h两组患者的视觉模拟评分（VAS），各时段自控硬膜外镇痛（PCEA）有效按压次数和不良反应。结果术后4、8、12hVAS评分A组明显低于B组（P〈0．05），两组不良反应的发生率比较差异无统计学意义（P〉0.05）。结论盐酸丁丙诺啡硬膜外超前镇痛能有效减轻子宫下段剖宫产术的术后疼痛。Objective To observe the effect of preemptive analgesia with epidural buprenorphine on the postoperative pain for patients who were undergoing cesarean section. Methods Eighty ASA I - 11 patients underwent selective cesarean section under combined spinal epidural analgesia were randomly divided into two groups ： preemptive analgesia group （ group A, n = 40） and control group （ group B, n = 40）. Ten minutes before operation, the patients in group A received epidural injection of buprenorphine 0. 15 mg and group B received normal saline 4 ml. The analgesia effect was assessed by visual analogue scale（VAS） at 4, 8, 12, 24, 48 hours after operation, side effects and effective pressing times of PCEA were also recorded. Results The VAS scores of group A were significantly lower than those of group B at 4,8 and 12 hours after operation（ P 〈0. 05）. The incidence of side effects in the two groups was not significant（ P 〉 0. 05）. Conclusions Preemptive analgesia with epidural buprenorphine can provide saris- factory pain relief with no obvious side effects after lower uterine segment cesarean section.

关 键 词：盐酸丁丙诺啡 超前镇痛 子宫下段剖宫产术 

分 类 号：R614[医药卫生—麻醉学]