单分散高分子微球的制备及色谱性能  

Preparation and Chromatographic Characterization of Monodisperse Polymeric Microspheres

作　　者：马言顺[1] 王子[1] 吴珊[1] 胡锐[1] 

机构地区：[1]四川师范大学化学与材料科学学院,四川成都610068

出　　处：《精细化工》2013年第3期299-302,共4页Fine Chemicals

基　　金："先进功能材料"四川省高校重点实验室开放课题(KFKT2010-04)~~

摘　　要：以二乙烯基苯(DVB-55)和二乙二醇二甲基丙烯酸酯(DGD)为共聚单体,采用沉淀聚合法在乙腈溶剂中一步制得了聚(二乙烯基苯-co-二乙二醇二甲基丙烯酸酯)微球[P(DVB-DGD)]。用FTIR、SEM和BET等方法对P(DVB-DGD)进行表征,结果表明,两种单体在聚合过程中实现了共聚,数均粒径为3.6μm的单分散微球表面未见大孔结构,微球比表面积为2.9 m2/g,平均孔径为9.1 nm。以两组试样为探针分子,采用反相液相色谱模式考察了P(DVB-DGD)填充的新型固定相的色谱性能,结果显示,组分获得了尖锐对称的峰形。色谱柱呈现了较高柱效和良好色谱性能,表明沉淀聚合在HPLC固定相方面具有较好应用前景。Poly （ divinylbenzene-co-diethylene glycol dimethacrylate ） [ P （ DVB-DGD ） ] microspheres were prepared by precipitation polymerization in acetonitrile solvent with divinylbenzene -55 and diethylene glycol dimethacrylate as comonomers. FTIR, SEM and BET were applied to characterize P （DVB-DGD）. FFIR shows that the two monomers copolymerized during the precipitation polymerization process. SEM indicates that no macroporous structure could be observed and the number-average diameter of the monodisperse microspheres was 3.6 μm. The surface area and the average pore diameter of P（DVB-DGD） were 2.9 m^2/g and 9. 1 nm, respectively. With the two samples as probes, the chromatographic performance of the novel stationary phase packed with P （DVB-DGD） was evaluated by reversed-phase liquid chromatographic mode. The chromatographic results show that the peak shape of the analytes was sharp and symmetric. The column exhibited high column efficiency and excellent chromatographic performance, which indicates that precipitation polymerization holds out bright prospect of application in stationary phase used in HPLC.

关 键 词：沉淀聚合法 微球 单分散 固定相 催化与分离提纯技术 

分 类 号：TQ322.4[化学工程—合成树脂塑料工业] O657.72[理学—分析化学]