重症手足口病院前急救的干预研究  

Emergency interventions on severe hand-foot-mouth disease in children before admission to hospital

作　　者：乃远福[1] 冯尚克[2] 崔小锋[1] 肖玉光[1] 黄永义[1] 黄雪红[1] 

机构地区：[1]百色市人民医院急诊科,广西百色533000 [2]百色市人民医院儿科,广西百色533000

出　　处：《中华医院感染学杂志》2013年第5期1097-1099,共3页Chinese Journal of Nosocomiology

摘　　要：目的分析重症手足口病院前急救的干预方法,为该病的急救提供科学参考。方法选择2010年9月-2012年8月接受干预方法的50例重症手足口病患儿为观察组,并选择2009年1月-2010年6月未接受干预方法的75例重症手足口病患儿为对照组,使用多参数监护仪检测所有患者的体温、血压、心率、呼吸频率和血氧饱和度。结果观察组患者转运到达医院的平均体温(38.9±0.2)℃、血压(88.5±1.5)/(68.3±3.5)mm Hg、心率(160.9±43.4)次/min、呼吸频率(55.7±11.1)次/min和血氧饱和度(92.2±8.4)%,与转运前差异无统计学意义;对照组患者转运到达医院的上述参数,均显著高于转运前(P<0.05);观察组转运途中有2例发展为危重型,无死亡,对照组有21例发展为危重型,2例死亡。结论重型手足口病患儿在转运途中应用甲泼尼龙、甘露醇和人免疫球蛋白联合干预对防止发展为危重型手足口病,减少患者死亡有重要意义。OBJECTIVE To analyze the emergency interventions on severe hand-foot-mouth disease in children before they are enrolled to the hospital so as to provide scientific basis for emergency treatment of this diseases.METHODS A total of 50 patients with severe hand foot mouth disease,who received the intervention methods from Sep 2010 to Aug 2012,were selected as the observation group,and 75 patients with severe hand-foot-mouth diseases,who did not receive the intervention methods from Jan 2009 to Jun 2010,were set as the control group.Multi-parameter monitor was used to measure the body temperature,blood pressure,heart rate,respiratory rate,and oxygen saturation of all the patients.RESULTS The temperature（38.9±0.2）℃,systolic pressure（88.5±1.5）mmHg,diastolic pressure（68.3±3.5）mmHg,heart rate（160.9±43.4）beats/min,respiratory rate（55.7±11.1）times /min and blood oxygen（92.2±8.4）% of the patients after being transported to the hospital have no significant difference with those of the patients before being transported to the hospital in the observation group.However,there were significant differences in the parameters in the control group（P0.05）.There were 2 patients who developed to the critically severe type and no death case in the observation group,and there were 21 patients who developed to the critically severe type and 2 death cases in the control group.CONCLUSION Methylprednisolone,mannitol and human immune globulin combined intervention can prevent the development from severe hand-foot-mouth disease to critically severe hand-foot-mouth disease in the children in transit,with great significance in reducing the mortality.

关 键 词：手足口病 甲泼尼龙 甘露醇 人免疫球蛋白 

分 类 号：R181.3[医药卫生—流行病学]