炙甘草汤中麦冬总皂甙及其配伍对心肌生理特性的影响  

The lnfluences of Ophiopogan total saponies(OTS) and lts Combination of Zhigancao Decoction on Myocardium Physiological Properties

作　　者：陈兰英[1] 陈奇[1] 刘荣华[1] 毕明[1] 朱乐凯 

机构地区：[1]江西中医学院,南昌330006

出　　处：《中国实验方剂学杂志》2000年第4期30-32,共3页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：国家自然科学基金!(3986 0 0 84);江西省自然科学基金!(945 35 )

摘　　要：实验结果显示三种成分配伍作用优于两两配伍 ,两两配伍作用又强于单个作用 ,并且作用随麦冬总皂甙浓度增高而加强 ,当甘草酸 ,人参总皂甙和麦冬总皂甙按 0 .384、0 .144、0 .12 0 mg/ml组方时 ,明显降低大鼠离体右心房肌自律性和左心房肌兴奋性 ,明显延长左心房肌功能不应期 (FRP)The results showed that the group combined by three ingredients was more potent than one combined by two ingredients or each igredient with concentration dependent relationship.When the ratio of GA,GTS and OTS was 0 384∶0 144∶0 120,the combined group significantly decreased automaticity of isolated rat's right atrium,obviously inhibited excitability and prolonged the functional refractory period of isolated rat's left atrium.

关 键 词：炙甘草汤 麦冬总皂甙 配伍 心肌生理特征 中药 

分 类 号：R285.5[医药卫生—中药学] R284.1[医药卫生—中医学]