中西医结合疗法对白内障超声乳化术后并发症的防治效果分析  

Clinical Efficacy of Combined Therapy of Traditional Chinese Medicine and Western Medicine on Complications of Phacoemulsification

作　　者：马红蕾[1] 卫玉彩[1] 段佳良[1] 盛梦怡[1] 闫雪梅[1] 戴丽[1] 

机构地区：[1]河北医科大学第二医院眼科,石家庄050000

出　　处：《中国实验方剂学杂志》2013年第6期326-329,共4页Chinese Journal of Experimental Traditional Medical Formulae

摘　　要：目的:探讨中西医结合疗法对白内障超声乳化术后并发症防治的临床疗效。方法:96例白内障超声乳化术后患者随机分为观察组和对照组各48例。对照组60只眼,采用妥布霉素地塞米松眼膏,1次/4～6 h;普拉洛芬滴眼液,1次/2～4h;盐酸左氧氟沙星滴眼液,1次/2～4 h。共4周。观察组62只眼,在对照组的基础上加用自拟清肝明目方内服,1剂/d,共8周。于术后1 d,1,8,12,24周观察患者视力,前房反应,角膜内皮细胞计数,后发性白内障发生率及残余皮质吸收情况。结果:术后1,8,12及24周观察组视力恢复均优于对照组(P<0.01);术后1,8周观察组前房反应情况均轻于对照组(P<0.01);术后1,8,12及24周角膜内皮细胞数量均多于对照组(P<0.01);观察组术后8,12及24周后发性白内障发生率均低于对照组(P<0.05);观察组术后1,8,12及24周皮质吸收情况均明显优于对照组(P<0.05,P<0.01)。结论:采用中西医结合疗法能抑制白内障超声乳化术后前房反应,促进角膜内皮细胞的再生,促残余皮质吸收,减少后发性白内障发生率,促进视力的恢复。Objective： To explore the clinical efficacy of combined therapy of traditional Chinese medicine and western medicine on complications of phacoemulsification. Method： Ninety-six patients performed routine phacoemulsification surgery were randomly divided into observation group （n=48） and control group （n=48）.There were 60 eyes in the control group, which were treated with bramycin dexamethasone oculentum （interval between application：4-6 h）, pranoprofen eye drops（interval between application： 2-4 h） and levofloxacin hydrochloride eye drops （interval between application： 2-4 h） for 4 weeks.There were 62 eyes in the observation group, on the basis of the western medicines in control group, patients in the observation group were orally taken Qinggan Mingmu Fang, 1 dose daily for 8 weeks.The eyesight, anterior chamber reaction, corneal endothelial count, posterior capsule opacification incidence and the residual cortical absorption were observed at 1 d, 1, 8, 12, 24 weeks after surgery. Result： The recovery of eyesight in the observation group was better than the control group at 1, 8, 12, 24 weeks after surgery（P〈0.01）.The anterior chamber reaction in the observation group was lower than that in the control group at 1, 8 weeks after surgery（P〈0.01）.The corneal endothelial counts in the observation group were higher than the control group at 1, 8, 12, 24 weeks after surgery（P〈0.01）.The rate of occurrence of after-cataract in the observation group was lower than that in the control group at 8, 12, 24 weeks after surgery（P〈0.05）.The cortical absorption in the observation group was superior to the control group at 1, 8, 12, 24 weeks after surgery（P〈0.05, P〈0.01）. Conclusion： Combination of Chinese and western medicine could suppress anterior chamber reaction after phacoemulsification, facilitate corneal endothelial cells regeneration, improve residual cortical absorption, decrease rate of occurrence of after-cataract and promote eyesight recovery.

关 键 词：白内障 超声乳化术 并发症 中西医结合疗法 

分 类 号：R281[医药卫生—中药学]