新生儿缺氧缺血性脑病医院感染原因分析  

Risk factors for nosocomial infections in neonates with hypoxic-ischemic encephalopathy

作　　者：李卫东[1] 谢巧庆[2] 迟春昕[1] 简赵芳[1] 王文祥[1] 

机构地区：[1]南方医科大学附属小榄医院儿科,广东中山528415 [2]中山大学附属第一医院新生儿科,广东广州510080

出　　处：《中华医院感染学杂志》2013年第6期1395-1396,共2页Chinese Journal of Nosocomiology

摘　　要：目的探讨新生儿缺氧缺血性脑病(HIE)医院感染的临床特点及原因,以便减少医院感染的发生。方法对医院新生儿科2008年1月-2011年12月收治的156例HIE患儿进行回顾性分析。结果 156例HIE中发生医院感染42例,感染率为26.92%,其中轻度HIE 84例,发生医院感染20例,感染率为23.81%,中度HIE 53例,发生医院感染的12例,感染率为22.64%;重度HIE 19例,发生医院感染10例,感染率为52.63%,发生医院感染的危险是轻度HIE的2倍。结论 HIE医院感染发生率比新生儿患儿总的医院感染率高,皮肤黏膜感染是其常见的感染原因,重度HIE易发生医院感染,HIE临床最佳治疗时间为6h。OBJECTIVE To explore the clinical characteristics and causes of nosocomial infections in the neonates with hypoxic-ischemic encephalopathy （HIE） so as to reduce the incidence of nosocomiaI infections. METHODS The clinical data of 156 cases of neonates with HIE who were treated in the neonatal department from Jan 2008 to Dec 2011 were retrospectively analyzed. RESULTS Of totally 156 neonates with HIE, the nosocomial infections occurred in 42 cases with the incidence rate of 26. 92%; there were 84 cases with mild HIE, among which there were 20 cases with nosocomial infections; there were 53 （23.81%） cases with medium HIE among which there were 12 （22.64%） cases with nosocomial infections; and there were 19 cases of severe HIE among which there were 10 cases with nosocornial infections , the incidence rate was 52. 63%, two times of the incidence of the nosocomial infections as the slight HIE. CONCLUSION The incidence rate of the nosocomial infections in the HIE neonates is higher than the total infection rate, the skin and mucous membrane infections is a common cause, the neonates with the severe HIE are prone to be infected, and the most appropriate time for the treatment of HIE is 6h.

关 键 词：新生儿 缺氧缺血性脑病 医院感染 

分 类 号：R722.19[医药卫生—儿科]