10%氟虫腈悬浮剂的配方优化及物理稳定性分析  

Development and Physical Stability Analysis of Fipronil 10% SC

作　　者：蔡梦玲[1] 马超[1] 徐妍[1] 王佳[1] 吴学民[1] 

机构地区：[1]中国农业大学理学院应用化学系,北京100193

出　　处：《农药》2013年第3期188-191,共4页Agrochemicals

基　　金：国家"十二五"科技支撑计划项目(2011BAE06A06-10)

摘　　要：[目的]优化氟虫腈悬浮剂配方,防治卫生害虫。[方法]通过湿式超微粉碎法制备10%氟虫腈悬浮剂,并通过流点法及配方法逐步筛选分散剂种类,优化润湿分散剂比例。[结果]10%氟虫腈悬浮剂的最优配方为氟虫腈10.0%(质量分数),烷基萘磺酸盐缩聚物(Morwet D-425)1.5%,烷基萘磺酸盐与阴离子润湿剂混合物(MorwetEFW)1.0%,黄原胶0.1%,硅酸镁铝0.5%,乙二醇5.0%,水补足至100%。[结论]该制剂经(54±2)℃热贮14 d后,其析水率、粒度分布和流变学性质均较好,其他各项指标均符合悬浮剂相关标准。The fipronil SC was researched to prevent sanitary insect pest.[Methods] Wet milling was adopted during the preparation of fipronil 10% suspension concentrate（sc）.The dispersant was screened through flow point method and formula method and the ratio of dispersant and wetting agent was optimized.[Results] The best formula after screening was showed below： fipronil 10.0%（mass ratio）,Morwet D-425 2.0%,Morwet EFW 1.0%,xanthan gum 0.1%,magnesium aluminium silicate 0.5%,ethylene glycol 5.0% and water was added to 100.0%.[Conclusions] The behaviour of the formula agreed fairly well with the experimentally relevant determined standards.After treatment of（54±2） °c for fourteen days,the rheological properties,drain rate and particle size distribution proved to be fine.

关 键 词：氟虫腈 悬浮剂 流变学 物理稳定性 

分 类 号：TQ453.2[化学工程—农药化工]