基于扩散理论的脉搏血氧测量系统  

A Pulse Oximetry System Based on Diffusion Theory

作　　者：高峰[1,2] 陈玮婷[1] 周晓青[1] 刘明[1] 张书颖[1] 赵会娟[1,2] 

机构地区：[1]天津大学精密仪器与光电子工程学院,天津300072 [2]天津市生物医学检测技术与仪器重点实验室,天津300072

出　　处：《纳米技术与精密工程》2013年第2期123-128,共6页Nanotechnology and Precision Engineering

基　　金：国家高技术研究发展计划(863计划)资助项目(2009AA02Z413);国家自然科学基金资助项目(30970775;81101106;61108081)

摘　　要：为了对低血氧饱和度进行准确测量,采用光子扩散方程模型替代传统的朗伯-比尔定律模型来推导血氧饱和度与特征值R之间的关系,并得到相应的定标曲线,从而克服了朗伯-比尔定律模型所固有的忽略散射效应这一问题及其所导致的较低的测量精度;在此基础上搭建了以数字信号处理器为核心处理设备的脉博血氧测量系统,并进行了手指阻断定性实验和低血氧饱和度水平下的仿体定量实验.实验结果表明,基于光子扩散方程模型的测量系统能够有效地反映出组织体血氧饱和度值的变化趋势;在低血氧饱和度情况下,采用扩散方程模型求得的结果较传统的朗伯-比尔定律模型获得的结果准确性提高了20%以上.该方法有望应用于低血氧饱和度的准确测量.In order to overcome the inherent drawbacks of Lambert-Beer＇s Law, which ignores the scattering effect and thus leads to a poor measurement precision, especially for low oxygen saturation, a study on the accurate measurement of low oxygen saturation was conducted in this paper. The photon diffusion theory was employed to achieve the calibration curve between oxygen saturation and the eigenvalue R rather than Lambert-Beer＇s Law. A pulse oximetry system using digital signal processer as core device was set up based on the above theory. A finger blocking-up qualitative experiment and a series of quantitative phantom experiments were performed under low oxygen saturation. The results demonstrate that the measurement system based on photon diffusion theory can effectively provide the variation trends of oxygen saturation in tissue, and that there is an improvement of 20% in accuracy compared with Lambert-Beer＇s Law theory when low oxygen saturation is measured. The approach pro- posed in this paper offers a promising tool for the accurate measurement of low oxygen saturation.

关 键 词：血氧饱和度 扩散方程 数字信号处理 测量系统 

分 类 号：R318.51[医药卫生—生物医学工程]