阿托品和L-天仙子胺的太赫兹光谱分析  

Terahertz Time-Domain Spectroscopic Investigation of Atropine and L-Hyoscyamine

作　　者：付秀华[1] 张文婷 赵容娇[1] 杜勇[1] 李向军[1] 洪治[1] 

机构地区：[1]中国计量学院机电工程系太赫兹技术与应用研究所 [2]浙江省食品药品检验研究院,杭州市310004

出　　处：《光谱实验室》2013年第2期952-955,共4页Chinese Journal of Spectroscopy Laboratory

基　　金：浙江省自然科学基金(Y2110690)

摘　　要：利用太赫兹时域光谱技术(THz-TDS)在室温(298K)和低温(90K)下对阿托品和L-天仙子胺在0.2—1.8THz范围内进行了光谱测量,发现阿托品和L-天仙子胺在太赫兹波段存在各自明显的特征吸收峰,可作为其在THz波段的指纹谱。该研究结果为快速无损鉴别左旋体L-天仙子胺和其消旋体阿托品提供了一种新的检测手段。The absorption spectra of atropine and L-hyoscyamine were measured in 0.2-1.8THz using terahertz time-domain spectroscopy （THz-TDS） at Temperature of 298K and 90K,respectively. Experimental results indicate that atropine and L-hyoscyamine both have distinct absorption features in the THz region,which can be used as fingerprints for the molecular recognition. This work provides a new method to detect the levorotatory form L-hyoscyamine and raeemate atropine quickly and safely.

关 键 词：太赫兹光谱 阿托品 L-天仙子胺 

分 类 号：R917[医药卫生—药物分析学] O433[医药卫生—药学]