钛表面FHA-SrHA双相生物陶瓷涂层的制备及性能  

Fabrication and properties of FHA/SrHA biphasic coating on titanium substrate

作　　者：冯芳芳[1] 尹乒[2] 雷霆[1] 吕凝磊[1] 

机构地区：[1]中南大学粉末冶金国家重点实验室,长沙410083 [2]中南大学湘雅医院,长沙410008

出　　处：《粉末冶金材料科学与工程》2013年第1期72-77,共6页Materials Science and Engineering of Powder Metallurgy

基　　金：国家自然科学基金委员会创新研究群体基金资助项目(51021063);中南大学粉末冶金国家重点实验室开放基金资助项目

摘　　要：在经过碱热处理的纯钛表面采用溶胶-凝胶法和提拉涂覆法制备含氟羟基磷灰石(FHA)-锶取代羟基磷灰石(SrHA)双相生物陶瓷涂层。采用X射线衍射检测涂层的相组成,采用扫描电镜观察涂层的形貌,采用划痕法测定涂层与基体的结合力。结果表明:所制备的涂层是均匀和致密的FHA-SrHA双相涂层;与单相FHA和SrHA涂层相比,FHA-SrHA双相涂层与钛基体的结合力明显优于SrHA涂层,略低于FHA涂层;TRIS溶液中的溶解性实验结果显示3种涂层均发生溶解和钙磷酸盐的重沉积过程,表现出良好的生物活性,但FHA-SrHA双相涂层的溶解速率远远低于单相FHA及SrHA涂层,这表明可以通过双相涂层设计来提高生物陶瓷涂层材料的植入寿命和稳定性。Colloidal sol-gel derived Fluor-hydroxyapatite （FHA） and strontium-substituted hydroxyapatite （SrHA） biphasic coating （FHA-SrHA） was prepared on a titanium substrate by alkali-heat-treatment. The phase composition of the coating was analyzed by X-ray diffraction, surface morphology and structure of the coating were observed by scanning electron microscope, the adhesion strength of the coating was analyzed by scratching test. The results show that the obtained FHA-SrHA coating is uniform, dense and biphasic. The biphasic film exhibits superior adherence to the titanium substrate in comparison to the single SrHA coating, but inferior adherence to the single FHA coating. Solubility experiment in TRIS solution shows that FHA, SrHA and FHA-SrHA coatings proceeded a process of dissolving and re-precipitating calcium phosphate. However, the dissolution rate of the biphasic FHA-SrHA coating is much lower than that of FHA and SrHA coating, which suggests the possibility of extending the planting period by designing biphasic coating of FHA-SrHA.

关 键 词：溶胶-凝胶 含氟羟基磷灰石(FHA) 锶取代羟基磷灰石(SrHA) 双相涂层 溶解性 

分 类 号：TG139[一般工业技术—材料科学与工程]