中药生发擦剂治疗雄激素性脱发的实验研究  

Traditional Chinese Medicine Treatment of The Model of Androgenetic Alopecia

作　　者：李荣群[1] 卜夏威[1] 景佐[1] 

机构地区：[1]浙江中医药大学,浙江杭州310053

出　　处：《中华中医药学刊》2013年第3期552-554,I0006,共4页Chinese Archives of Traditional Chinese Medicine

基　　金：浙江省教育厅资助项目(2010-26)

摘　　要：目的:观察所选中药擦剂对雄激素性脱发模型的治疗作用。方法:在所建立的大鼠脱发模型上用所选中药擦剂分高、低浓度剂量涂于背部患处,观察记录大鼠背部毛发生长情况,通过测定血清雄激素的含量以及皮肤HE染色切片,综合分析该中药擦剂对毛发生长和毛囊形态结构的影响。结果:与模型组相比,药物治疗组的毛发生长毛囊恢复生长,且高浓度组较低浓度效果更佳明显。结论:该中药擦剂具有治疗作用。Objective：To observe the therapeutic effects of selected traditional Chinese medicine liniment on the model of androgenetic alopecia.Methods：On the basis of the established rat hair loss model,Take selected traditional Chinese medicine liniment,Divided into high and low concentration dose,and smear in the back surface of the skin.Observing,and recording the growth of hair in rats＇back.By measuring the content of serum androgens and Observing the skin HE dyeing slice,analyse the influence made on the hair growth and the morphological of hair follicle comprehensive.Results：Compared with model group,the hair and hair follicles of drug therapy group grow again and the effect of the treatment in high concentration is more significant than it in low concentration.Conclusion：he traditional Chinese medicine liniment has a therapeutic effect.

关 键 词：中药擦剂 雄激素性脱发 

分 类 号：R285.5[医药卫生—中药学]