栀子三萜类化学成分研究  

Studies on the Chemical Components of Triterpenoids of Gardenia jasminoides Ellis

作　　者：张忠立[1] 左月明[1] 罗光明[1] 付小梅[1] 蔡财军[1] 王彦彦[1] 

机构地区：[1]江西中医学院药学院,江西南昌330006

出　　处：《时珍国医国药》2013年第2期338-339,共2页Lishizhen Medicine and Materia Medica Research

基　　金：国家科技部"十二五"科技支撑计划课题(No.2011BAI04B01)

摘　　要：目的研究栀子Gardenia jasminoides Ellis.的干燥成熟果实中的三萜类化学成分。方法采用各种柱色谱方法分离纯化,通过理化常数测定和光谱分析鉴定三萜类化合物的结构。结果从栀子的果实中分离鉴定了10个三萜类化合物,分别为豆甾醇(1),豆甾醇-3-O-β-D-葡萄糖苷(2),19α-羟基-3-乙酰-乌苏酸(3),栀子花乙酸(4),3-乙酰-栀子花甲酸(5),β-谷甾醇(6),胡萝卜苷(7),熊果酸(8),3α-羟基-熊果酸(9),常春藤皂苷元(10)。结论化合物4,5,9和10为首次从该植物中分离得到。ObjectiveTo investigate the Chemical Components of triterpenoids of Gardenia jasminoides Ellis. MethodsVarious column chromatography were used in the isolation and purification,and physiochemical constant determination and spectral analysis were adopted to determine the chemical structures of triterpenoids. ResultsTen triterpenoids were isolated from Gardenia jasminoides Ellis stigmasterol（1）,stigmasterol-3-O-β-D-glucopyranoside（2）,19α-hydroxy-3-acetylursolic acid（3）,gardenolic acid B（4）,3-acetyl-gardenolic acid A（5）,β-sitosterol（6）,daucosterol（7）,ursolic acid（8）,3α-hydroxy-ursolic acid（9）,hedera genin（10）. ConclusionCompounds 4,5,9 and 10 were first isolated from this plant.

关 键 词：栀子 化学成分 三萜类 

分 类 号：R284.1[医药卫生—中药学]