N-烷基葡萄糖酰胺的合成工艺研究  

Study on synthesis process conditions of N-alkyl glucose amide

作　　者：王丽艳[1] 范琳琳[1] 佟白[1] 徐群[1] 高万寿[1] 董国文[1] 

机构地区：[1]齐齐哈尔大学化学与化学工程学院,黑龙江齐齐哈尔161006

出　　处：《印染助剂》2013年第3期9-11,共3页Textile Auxiliaries

基　　金：黑龙江省教育厅科学技术项目(12511591)

摘　　要：以D-葡萄糖酸-δ-内酯和脂肪胺(正辛胺、癸胺、十二胺、十四胺、十六胺、十八胺)为原料,合成了N-烷基葡萄糖酰胺.考察了反应时间、反应温度、n(D-葡萄糖酸-δ-内酯)∶n(脂肪胺)对反应的影响.通过单因素法确定了合成N-烷基葡萄糖酰胺的较佳工艺:n(D-葡萄糖酸-δ-内酯)∶n(脂肪胺)=1∶1.1,甲醇作溶剂,60℃下反应3 h,收率均在90%以上.产物用IR、1H-NMR进行表征.结果表明,合成N-烷基葡萄糖酰胺的条件温和,操作简单,收率较高.The N-alkyl glucose amine was synthesized from D-glucose acid-8-1actone and aliphatic amine （octylamine, decylamine, dodecylamine, tetradecyamine, hexadecylamine, octadecylamine）. The influenc- es of reaction time, reaction temperature and molar ratio of D-glucose acid-8-1actone to aliphatic amine were investigated. The optimized synthesis conditions of N-alkyl glucose amine were determined through the single factor experiment： the molar ratio of D-glucose acid-8-1actone to aliphatic amine was 1：1.1, reacted at 60℃ for 3 h, and the yield was higher than 90%. The product was characterized by IR and 1H-NMR. The re- sults showed that the synthesis conditions of N-alkyl glucose amide were mild, simple operated and high yield.

关 键 词：N-烷基葡萄糖酰胺 单因素法 合成 表征 

分 类 号：TQ423.2[化学工程]