类风湿关节炎实验室指标变化与瘀证的相关性研究  

Study on Relationship between Rheumatoid Arthritis and Laboratory Indexes and Blood Stasis Syndrome

作　　者：靖卫霞[1] 鲁丽 朱跃兰[3] 

机构地区：[1]北京中医药大学,北京100078 [2]云南省中医院,云南昆明650002 [3]北京中医药大学东方医院,北京100078

出　　处：《中医学报》2013年第3期420-422,共3页Acta Chinese Medicine

基　　金：云南省科技厅自然基金项目(编号:2006XFX02)

摘　　要：目的:探讨类风湿关节炎实验室指标变化与瘀证的相关性。方法:将100例患者依据中医辨证分型分为瘀证组52例和非瘀证组48例。观察两组实验室检测指标ESR、CRP、IgG、IgA、IgM、C3、C4、RF-IgG、RF-IgA、RF-IgM、AKA、抗CCP、PLT等变化情况。结果:瘀证组RF-IgG与IgM,RF-IgA与IgA,RF-IgM与PLT、ESR、IgM有显著相关性(P<0.01);RF-IgG与PLT、ESR、IgA,RF-IgA与PLT、CRP、ESR、IgM、C3,RF-IgM与C3、C4有明显相关性(P<0.05);非瘀证组RF-IgG与IgM有显著相关性(P<0.01),其余均无明显相关性(P>0.05)。结论:①实验室指标主要反映RA的疾病特点,而很难反映RA的证候特点,两组证候的RA患者,可表现出该病共同的相关实验室变化。②可以通过RF-IgG、RF-IgA、RF-IgM与PLT、ESR、CRP、IgG、IgA、IgM、C3、C4是否有明显或显著相关性来判断类风湿关节炎血瘀的程度。Objective：Correlation between the changes of ventricular index text of rheumatoid arthritis and stasis syndrome. Methods ：100 patients on the basis of TCM syndrome of blood stasis group 52 eases and non blood stasis syndrome group 48 eases. Observation of laboratory testing indexes of ESR, CRP, IgG, IgA, IgM, C3, CA, RF-IgG, RF-IgA, RF-IgM, AKA, KangCCP, PLT and other changes. Resuits ： Blood stasis syndrome group RF-IgG and IgM, RF-IgA and IgA, RF-IgM and PLT, ESR, IgM had significant correlation （ P 〈 O. O1 ） ;RF-IgG and PLT,ESR,IgA,RF-IgA and PLT,CRP,ESR,IgM,C3 ,RF-IgM and C3 ,C4 had significant correlation（P 〈0.05 ） ; Non blood stasis syndrome group RF-IgG and IgM had significant correlation（ P 〈0. O1 ） ,and the rest had no obvious correlation. Conelusion：①Laboratory indicator mainly reflects the features of RA disease but it is difficult to reflect the characteristics of the RA syndrome. Twogroups of syndrome in RA patients showed a correlation test chamber of the disease changes. ②Through RF-IgG, RF-IgA, RF-IgM and PLT,ESR, CRP, I gG, IgA, IgM, C3, C4 have significant or significant correlation to determine the degree of blood stasis in rheumatoid arthritis.

关 键 词：类风湿关节炎 实验室指标 瘀证 

分 类 号：R259.932.2[医药卫生—中西医结合]