PCI后非靶病变进展需再次PCI的危险因素  

Risk factors of non-target-lesion PCI in patients undergoing PCI

作　　者：张蕊[1] 巩会平[2] 张荃方[3] 王宏涛[3] 胡建[1] 辛辉[1] 

机构地区：[1]青岛大学医学院附属医院心内科,山东青岛266003 [2]山东大学第二医院心内科 [3]青岛大学医学院附属医院心电诊断科

出　　处：《临床心血管病杂志》2013年第3期209-211,共3页Journal of Clinical Cardiology

基　　金：山东省科技攻关计划(No:2007GG3W202055)

摘　　要：目的:探讨冠心病患者经皮冠状动脉(冠脉)介入治疗(PCI)术后因非靶病变进展致出现临床症状需再次行PCI治疗的危险因素及其可能机制。方法:选择2008-01-2010-12在青岛大学医学院附属医院经择期或急救PCI治疗并存活出院的冠心病患者697例,平均随访1年。根据是否因非靶病变进展致再次行PCI术,将入选患者分为非靶病变进展需行PCI组(PCI组)56例和非靶病变无进展组(无进展组)641例。收集并比较两组患者的临床资料及初次PCI时的冠脉造影结果。结果:与无进展组比较,PCI组糖尿病、血脂异常以及初次PCI时多支血管病变所占比例均明显增高(均P<0.05)。结论:糖尿病、血脂异常及冠脉多支病变是PCI后非靶病变进展需行PCI的高危因素。Objective： To explore the risk factors and the possible mechanisms of non-target-lesion PCI after initial PCI in patients with coronary heart disease （CHD）. Method： Our study comprised 697 CHD patients that treated with initial PCI from January 2008 to December 2010 in Affiliated Hospital of Medical College, Qingdao University. After followed up for 1 year, all the patients were divided into two groups according to whether needed non-target-lesion PCI after initial PCI or not. The non-target-lesion PCI group consisted of 56 patients while the nonprogressor group consisted of 641. Baseline information and coronary angiographic information was collected. Result： Compared with nonprogressor group, more patients with diabetes and hyperlipidemia were noted in nontarget-lesion PCI group （P〈0.05）. The proportion of multi-vessel disease was significantly higher in non-targetlesion PCI group than that in nonprogressor group （P〈0.05）. Conclusion： Diabetes, hyperlipidemia and multiple lesions were risk factors of non-target-lesion PCI after initial PCI.

关 键 词：冠心病 经皮冠状动脉介入治疗 非靶病变 

分 类 号：R541.4[医药卫生—心血管疾病]