两种长春花生物碱类药物临床护理对照观察  

Contrast observation of clinical nursing of two kinds drugs of vinblastine sulfate

作　　者：胡桂华[1] 罗霄[1] 陈声波[1] 

机构地区：[1]江西医学院第一附属医院肿瘤科,江西南昌330006

出　　处：《护士进修杂志》2000年第10期731-733,共3页Journal of Nurses Training

摘　　要：目的去甲长春碱（ＮＶＢ）和硫酸长春地辛（ＶＤＳ）临床应用中的反应进行对照观察和护理措施。方法对７１例恶性肿瘤患者应用ＮＶＢ或ＶＤＳ出现的胃肠道反应，骨髓抑制，神经末梢损伤、皮肤静脉损伤进行对照观察。结果两者的胃肠道反应，神经末梢损伤无显著性差异（Ｐ＞０．０５），骨髓抑制及皮肤静脉损伤比较两者有显著性差异（Ｐ＜０．０５）。结论临床护理要以化疗药物的不同副反应而采取相应的护理措施，以控制毒副反应的发生。Objective To contrast and observe the reaction of NVB and VDS and It's nursing measure. Method 71 cases of patients with malignancy were treated by NVB or VDS, the reaction such as gastric and intestinal reaction, marrow restrain, never acroteric Damage, skin vein damage were observed and compared. Results there is no significant difference on the gastric and intestinal reaction, never acroteric damage for the two kind of drug's treatment(P > 0.05). there is significant difference on marrow restrain and skin vein danage between the two(P<0.05). Conclusion Clinical nursing should adapt related nursing measure according to the side effect of different chemical drugs to control the occurrence of toxicity and side reaction.

关 键 词：临床护理 去甲长春碱 硫酸长春地辛 抗燥药 

分 类 号：R979.1[医药卫生—药品] R473.73[医药卫生—药学]