Arrestins作用的研究进展  

Progress studing in the role of arrestins

作　　者：陈厚昌[1] 张浚[1] 

机构地区：[1]第一军医大学药理学教研室,广州510015

出　　处：《中国药理学通报》2000年第4期377-380,共4页Chinese Pharmacological Bulletin

基　　金：国家自然科学基金资助课题 !No 395 70 82 7

摘　　要：Arrestins是继G 蛋白偶联受体激酶 (GRK)之后发现的另一个中介受体脱敏的重要可溶性蛋白。它不仅在受体脱敏 ,而且在受体胞吞 ,内部化 。Arrestin is an important soluble protein that mediates receptor desensitization which is found after G protein coupled receptor kinase(GRK).It plays an important role not only in receptor desensitization,but also in receptor endocytosis, internalization, resensitization and mitogenic signaling.

关 键 词：G-蛋白偶联受体激酶 ARRESTINS 受体脱敏 

分 类 号：R977.6[医药卫生—药品]