米非司酮联合甲氨蝶呤治疗宫外孕54例  

Mifepristone Combine with Methotrexate in Treating Ectopic Pregnancy in 54 Cases

作　　者：杨红英[1] 曾凡清[1] 吴南顺[1] 殷娟[1] 康楷[1] 

机构地区：[1]重庆市第九人民医院妇产科,重庆400700

出　　处：《中国药业》2013年第5期91-92,共2页China Pharmaceuticals

摘　　要：目的研究米非司酮联合甲氨蝶呤治疗宫外孕的疗效和不良反应,探讨其临床应用价值。方法回顾分析2010年5月至2012年5月间105例宫外孕患者的临床资料,其中甲氨蝶呤治疗51例(对照组),米非司酮联合甲氨蝶呤治疗54例(治疗组),比较两组疗效和不良反应。结果对照组和治疗组有效率分别是74.51%和81.48%,治疗组疗效高于对照组(P<0.05);对照组和治疗组不良反应发生率分别是11.76%和12.96%,差异无统计学意义(P>0.05)。结论米非司酮联合甲氨蝶呤治疗宫外孕疗效确切,值得临床推广。Objective To investigate the effect of mifepristone combine with methotrexate in treating ectopic pregnancy. Methods The clinical data of 105 patients with ectopic pregnancy between May 2010 and May 2012 were analyzed. Among them, 51 cases treated by methotrexate （control group）, and 54 cases treated by mifepristone combine with methotrexate （treat group）, then the effects and complication was observed. Results The effective power in treat group and control group were 74. 51% and 81.48% espectively. And the effective power in treat group was higher than that in control group（P 〈 0. 05）. The complication in treat group and control group were 11.76% and 12.96% espectively. And there was no statistically significant between two groups（P 〉 0.05）. Conclusion The combination of mifepristone with methotrexate is effective for treating ectopic pregnancy.

关 键 词：宫外孕 米非司酮 甲氨蝶呤 

分 类 号：R969.4[医药卫生—药理学] R979.2[医药卫生—药学]