1834例泌尿生殖道支原体感染及药敏结果分析  

Chlamydia and Mycoplasma infection of the genital tract in 1 834 female patients and drug sensitivity

作　　者：陈秋晴[1] 张庆华[1] 

机构地区：[1]武汉市中心医院妇产科,湖北武汉430014

出　　处：《中国病原生物学杂志》2013年第2期173-174,183,共3页Journal of Pathogen Biology

摘　　要：目的了解泌尿生殖系统支原体感染及药物敏感性。方法用解脲脲支原体和人支原体培养鉴别定量药敏试剂盒培养鉴别支原体及进行耐药性测定。结果 1 834例泌尿生殖道感染患者支原体阳性561例,感染率为30.59%;其中解脲脲支原体占79.86%,人支原体占3.57%,Uu合并Mh占16.58%。Uu对乙酰螺旋霉素、环丙沙星耐药,对交沙霉素、罗红霉素、克拉霉素等敏感。Mh对强力霉素、米诺霉素、交沙霉素敏感,对罗红霉素、红霉素、环丙沙星、克拉霉素高度耐药。Uu与Mh双重感染对交沙霉素敏感,对罗红霉素、红霉素、环丙沙星、克拉霉素和乙酰螺旋霉素几乎完全耐药。结论支原体对各种抗菌药物已产生一定的耐药性,在治疗支原体感染时应根据药敏结果合理使用药物。Objectives To examine urogenital tract infections caused by Mycoplasma and to determine Mycoplasma＇s sensitivity to antimierobials. Methods Ureaplasma urealyticum （Uu） and Mycoplasma hominis （Mh） were cultured and identified, and their drug sensitivity was tested. Results Of the 1 834 samples, 561 were positive （30.59%）. Of these, 79.86% had Uu, 3.57% had Mm, and 16.58% had Uu＋Mh. Drug sensitivity testing showed that Uu was most resistant to acetyl spiramycin and ciprofloxacin and was most sensitive to josamyein, roxithromycin, roxithromyein, and clarithromycin. Mh was most resistant to roxithromyein, erythromycin, clarithromycin, and ciprofloxaein and was most sensitive to doxycyeline, carubicin, and josamyein. Uu＋ Mh was most resistant to roxithromycin, erythromycin, clar- ithromyein, and eiprofloxacin and was most sensitive to Josamycin. Conclusion Mycoplasma produces particular resist-ance to antibiotics. Antibiotics should be chosen and used rationally in accordance with drug susceptibility.

关 键 词：泌尿生殖道 支原体感染 药敏试验 

分 类 号：R518.9[医药卫生—内科学]