地佐辛超前镇痛对无痛人工流产孕妇呼吸循环及苏醒时间的影响  

The effects of dezocine preemptive analgesia on cardiorespiratory and recovery time of painless induced abortion

作　　者：潘松[1] 徐晖[1] 张景俊[1] 吴鸿浩[1] 岳侃[1] 

机构地区：[1]安徽省蚌埠市第三人民医院麻醉科,233000

出　　处：《蚌埠医学院学报》2013年第2期151-153,共3页Journal of Bengbu Medical College

摘　　要：目的:探讨地佐辛超前镇痛在丙泊酚无痛人工流产麻醉中对孕妇呼吸循环及苏醒时间的影响。方法:将60例人工流产孕妇随机分为3组,在消毒前5 min分别静脉注射等量生理盐水(A组)、芬太尼1μg/kg(B组)、地佐辛(0.05 mg/kg)(C组),消毒后按2 mg/kg注入丙泊酚,孕妇意识消失(睫毛反射消失)后开始手术,术中根据需要追加丙泊酚每次20～40 mg。记录心率及基础值(T1)、麻醉后(T2)、手术中扩宫颈口时(T3)及术毕时(T4)脉搏血氧饱和度(SpO2)的变化,以及手术时间、苏醒时间、丙泊酚用量和术中麻醉效果。结果:C组患者术后心率低于术前(P<0.05),但无需处理;在T2时点,B组SpO2明显低于A、C组(P<0.01),在整个手术中B组SpO2均明显低于A、C组(P<0.01);A组丙泊酚用量最大(P<0.01),C组苏醒时间最短(P<0.01),A组麻醉效果均较B组和C组差(P<0.05)。结论:丙泊酚复合地佐辛(0.05 mg/kg)应用于人工流产术中较丙泊酚复合芬太尼及单独应用丙泊酚均更安全、有效,值得推广。Objective：To investigate the effects of dezocine preemptive analgesia on cardiorespiratory and recovery time of painless induced abortion with propofol. Methods： Sixty cases with painless induced abortion were randomly divided into group A, B and C. Group A, B and C were injected the same volume normal saline, fentanyl （ 1 ~g/kg） and dezocine （0.05 mg/kg） at the time of 5 minutes before sterilizing respectively and 2 mg/kg of propofol were injected after sterilizing. Operation began after patients consciousness disappear, and 20 - 40 mg of propofol were added as needed. The data of basic value（ T1 ）, after anesthesia（ T2）, surgery （ T3 ） and after surgery （ T4）, the operation and awakening time, the dosage of propofol and the grade of anesthesia effect were mesured. Results： The HR in group C postoperation were significantly lower that of preoperation （ P 〈 0.05 ）, but without further treatment. At T2, the values of SpO2 in group B were significantly lower than that in other two group （ P 〈 0.01 ）. The propofol consumption in group A were maximum, the recovery time in group C were the shortest and the anesthetic effects of group A were worse than that of group B and C （ P 〈 0.05 ）. Conclusions ： Compared with the effects of alone propofol, the application of dezocine combined with in painless induced abortion is safety and effect, which is worthy to be popularized.

关 键 词：人工流产 超前镇痛 地佐辛 丙泊酚 

分 类 号：R169.421[医药卫生—公共卫生与预防医学]