脑钠肽在COPD合并肺心病急性发作中的研究  

Study on Brain Natriuretic Peptide in AECOPD and Chronic Cor Pulmonale Patients

作　　者：周雨田[1] 马骄[2] 

机构地区：[1]四川省人民医院干部科老年疾病研究所呼吸病房,四川省成都市610072 [2]成都医学院检验医学院

出　　处：《医学理论与实践》2013年第5期571-572,共2页The Journal of Medical Theory and Practice

摘　　要：目的:探讨血脑钠肽水平在肺源性心脏病患者急性发作时及治疗后2周的变化并分析其临床意义。方法:75例COPD合并肺心病急性发作期患者在常规治疗前、后检测血中BNP及CRP水平及动脉血氧分压、二氧化碳分压。结果:治疗前的BNP及CRP水平均显著高于治疗后(P<0.01),治疗后PaO2较治疗前显著上升(P<0.05)。结论:COPD合并肺心病急性发作期患者血中BNP及CRP水平明显增高,可以作为急性发作及好转的指标。Objective：To evaluate the level of BNP in patients with chronic obstructive pulmonary disease（COPD） and chronic cor pulmonale.Methods：Before and after 14 days therapy,plasma BNP levels and blood gas analysis were detected in 75 patients with COPD and chronic cor pulmonale.Results：The serum BNP,CRP level before therapy were significantly higher than that of afer therapy（P＆lt;0.01）.After therapy,the PaCO2 level were significantly lower than pre-treatment（P＆lt;0.01）,the PaO2 after therapy were significantly higher than pre-treatment（P＆lt;0.05）.Conclusion：BNP and the CRP level in patients with acute COPD and chronic cor pulmonale were significantly higher.BNP and CRP level could be used as AECOPD and recovery index.

关 键 词：慢性阻塞性肺疾病 肺心病 脑钠肽 

分 类 号：R563[医药卫生—呼吸系统]