氩激光488nm波长与混合波长光动力治疗鲜红斑痣的比较研究  

Comparative Research on Mixed and 488nm Argon Laser PDT for Port Wine Stain

作　　者：周国瑜[1] 张志愿[1] 顾基中[1] 马继壮[1] 

机构地区：[1]上海第二医科大学附属第九人民医院口腔医学院口腔颌面外科,上海200011

出　　处：《上海口腔医学》2000年第3期173-174,共2页Shanghai Journal of Stomatology

摘　　要：目的　为探索氩激光光动力治疗鲜红斑痣 (PWS)更为安全的方法 ,比较了 488nm单波长和常用混合波长氩激光的疗效及不良反应。方法　随机选择 5 2例患者分为 2组分别采用 488nm单波长氩激光及混合波长氩激光进行治疗。结果　 488nm单波长激光组的治愈率为 19.2 3 % ,混合波长组为 11.5 4% ,两者无显著差异。总有效率分别为 92 .31% %及 88.46 % ,无统计学差异。不良反应的发生率为混合波长组高于单一波长组。结论　 488nm单波长氩激光光动力治疗与混合波长方法治疗疗效相同 。Objective In order to search a safer argon laser photodynamic method, this study used 488nm wavelength and common mixed spectrum argon laser PDT for treating Port Wine Stain. The therapeutic effects and side effect were compared.Methods Fifty two cases of PWS were divided into two groups randomly. Argon laser PDT by two ways of laser irradiation were used.Results Our data revealed 19.23% cure rate in 488 nm laser PDT group, while that of mixed wavelength laser group was 11.54%. There was no significant difference in the two groups. Also the effective rate of 488nm laser group was 92.31% and that of mixed group was 88.46%. But the difference was not significant statistically. Side effect occurred often in mixed spectrum laser group. That was 57.69% for mixed group, 38.46% for 488nm group.Conclusion Argon laser PDT at 488nm had the similar therapeutic result contrasted to mixed spectrum laser group, but it was safe.

关 键 词：激光波长 光动力效应 鲜红斑痣 氩激光 治疗 

分 类 号：R758.6[医药卫生—皮肤病学与性病学]