三维斑点追踪成像评价原发性高血压患者左心室整体收缩功能  

Assessment of Left Ventricular Systolic Function by Three-dimensional Speckle Tracking Imaging in Patients with Essential Hypertension

作　　者：李春艳[1] 朱文晖[2] 刘稳刚[2] 

机构地区：[1]南华大学附属南华医院超声室,湖南衡阳421002 [2]中南大学湘雅三医院超声科,湖南长沙410013

出　　处：《中国医学影像学杂志》2013年第3期197-200,205,共5页Chinese Journal of Medical Imaging

摘　　要：目的探讨三维斑点追踪成像(3D-STI)技术评价左心室不同构型原发性高血压(EH)患者左心室整体收缩功能的价值。资料与方法60例原发性高血压患者按照左心室不同构型分为左心室正常构型(LVN组,30例)和左心室重构型(LVR组,30例),选取30例健康志愿者作为对照。采用3D-STI技术获取各组左心室整体纵向收缩期峰值应变(GLS)、左心室整体径向收缩期峰值应变(GRS)、左心室整体圆周收缩期峰值应变(GCS)、左心室射血分数(LVEF),比较三组指标间的差异。结果与正常对照组比较,LVN组GLS减低(P<0.05),GCS、GRS无明显变化(P>0.05),LVR组GLS、GCS、GRS均减低(P<0.05);与LVN组比较,LVR组GLS、GCS、GRS均减低(P<0.05)。三组LVEF比较无显著差异(P>0.05)。结论 3D-STI技术通过评估EH患者左心室的三维整体应变,可敏感地反映左心室收缩功能的改变。EH患者在LVEF正常时已发生收缩功能改变,为临床治疗与疗效评价提供了参考依据。Purpose To explore the value of three-dimensional speckle tracking imaging （3D-STI） in evaluating systolic function in patients with essential hypertension of different left ventricular configurations. Materials and Methods Sixty patients with essential hypertension were divided into two subgroups based on left ventricular configuration including left ventricular normal group （LVN group, n=30） and left ventricular remodeling group （LVR group, n=30）. Thirty healthy volunteers were enrolled as controls. 3D-STI was used to obtain global left ventricular longitudinal peak systolic strain （GLS）, global left ventricular radial systolic peak strain （GRS）, global left ventricular circumferential peak systolic strain （GCS） and left ventricular ejection fraction （LVEF） of each group. Difference of each parameter among three groups was compared. Results Compared with the control group, GLS decreased in LVN group （P〈0.05）, GCS and GRS showed no significant change （P〉0.05）. GLS, GCS and GRS of LVR group decreased （P〈0.05）. Compared with LVN group, GLS, GCS and GRS decreased in LVR group （P〈0.05）. No significant difference in LVEF was seen among three groups （P〉0.05）. Conclusion 3D-STI technique can sensitively reflect the change of left ventricular systolic function in patients with EH by assessing global response of left ventricle. EH patients may have systolic function change with normal LVEF. 3D-STI technique provides a reference for clinical treatment and efficacy evaluation.

关 键 词：高血压 心室功能 左 超声心动描记术 多普勒 彩色 斑点追踪成像 

分 类 号：R544.1[医药卫生—心血管疾病] R445.1[医药卫生—内科学]