清利通淋汤体外和体内抗菌作用的实验研究  

Experimental Study on Antibacterial Effects of QingLi TongLinTang in Vitro and Vivo

作　　者：潘文[1] 康开彪[1] 王煜[2] 张参军[2] 马骏[3] 

机构地区：[1]甘肃省中医药研究院,甘肃兰州730050 [2]甘肃省中医院 [3]甘肃中医学院

出　　处：《西部中医药》2013年第3期22-24,共3页Western Journal of Traditional Chinese Medicine

基　　金：甘肃省中医药科研项目(编号2006-23);甘肃省中青年科技基金计划项目(编号0806RJYA011)

摘　　要：目的:探讨清利通淋汤体外、体内的抗菌作用。方法:采用液体试管抑菌法和小鼠腹腔感染法,观察清利通淋汤体外和体内抑菌作用。结果:清利通淋汤对金黄色葡萄球菌、大肠埃希氏菌均有不同程度的抑菌作用,MIC分别为62 mg/mL和31 mg/mL;可使腹腔感染金黄色葡萄球菌小鼠和腹腔感染大肠埃希氏菌小鼠的死亡数明显降低,保护率(%)明显提高。结论:清利通淋汤有明显的体内、体外抗菌作用。Objective： To discuss antibacterial effects of QingLi TongLinTang in vitro and vivo. Method： Antibacterial effect of QingLi TongLinTang in vitro and vivo was observed with the methods of liquid tube test and abdominal infection of mice. Result： Experiments of QingLi TongLinTang presented bacteriostasis in different levels against staphylococcus aureus and Escherichia coli, the minimum inhibitory concentrations （MIC） were 62 mg/mL and 31 mg/mL respectively; which could reduce the death of mice suffering from peritoneal infection of taphylo- coccus aureus and Escherichia coli, also improve the protection rate significantly. Conclusion： QingLi TongLinTang possesses significant antibacterial effect in vitro and vivo.

关 键 词：清利通淋汤 抗菌 动物实验 

分 类 号：R285.5[医药卫生—中药学]