骨组织生物磁性及磁场生物学效应研究  

Research Progress on Biomagnetism and Biomagnetic Effect of Bone

作　　者：丁冲[1] 陈晓虎[1] 李迪杰[1] 宁旦旦[1] 商澎[1] 

机构地区：[1]西北工业大学生命学院,陕西西安710072

出　　处：《常州大学学报（自然科学版）》2013年第1期20-24,共5页Journal of Changzhou University：Natural Science Edition

基　　金：国家自然科学基金项目资助(51147008)

摘　　要：骨组织是一种整体表现抗磁性的生物活性物质,外加磁场具有促进骨组织生长的作用。临床上应用一定参数的脉冲磁场、静磁场进行骨质疏松、骨折愈合的治疗,并开发磁性骨植入材料促进骨修复。骨组织磁生物学效应的研究在整体、细胞、分子等多个层面开展,不同的骨组织细胞对磁场产生不同的响应。对各种骨细胞细胞磁性来源进行分析和检测,将为骨组织磁生物效应的机制及其应用提供指导和帮助。The magnetic properties of bone tissue are mainly dominated by the diamagnetic materials, which can act with the external magnetic fields. With the function of promoting bone growth, puls-electromagnetic fields （PEMFs） or static magnetic fields （SMFs） with certain parameters can be used as a therapy for the osteoporosis and fracture healing in clinical application, as well as the bone implant materials with magnetic property are developed to promote the damaged tissues repair. The research of effect of magnetic fields on bone tissue are studied on integration, cell, and molecular level. The osteoblast, osteoclast and osteocyte＇s responses to the same magnetic fields are different. To analysis and detect the magnetism of bone cells and bone tissue will provide a guidance for research the mechanism of biomagnetic effects of bone and its application.

关 键 词：磁场 抗磁性 成骨细胞 破骨细胞 骨细胞 

分 类 号：R318[医药卫生—生物医学工程]