早产儿肾功能特点及影响因素  

Renal Function in Preterm Neonates and the Influencing Factors

作　　者：韦露明[1] 钟丹妮[1] 

机构地区：[1]广西医科大学第一附属医院儿科,南宁530021

出　　处：《医学综述》2013年第5期854-856,共3页Medical Recapitulate

基　　金：广西壮族自治区卫生厅自筹经费科研课题青年基金(Z2012063)

摘　　要：早产儿肾功能不成熟,出生后早期由于受母体肌酐水平的影响及肾小管功能不成熟,其血清肌酐水平是增高的;肾小球滤过率低,在某些病理情况下易发生肾衰竭;肾小管功能差,易发生水电解质紊乱和酸碱平衡失调。早产儿出生后最初几周,肾功能经历了一个快速成熟的时期,并受胎龄、药物、营养、宫内发育情况、出生体质量等因素的影响。The renal function is immature in preterm neonates.The serum creatine is increasing during the early neonatal period due to the influence of maternal creatine concentration and the immaturity of tubular function.The glomerular filtration rate is low,so it is susceptible for preterm neonates to develop renal failure in some pathological condition during the first days of life.The tubular function is less mature,so preterm neonates are susceptible to be error in regulation of fluid,electrolyte and acid-base balance.Renal function undergoes rapid maturation in the early weeks after birth in preterm infants.The renal function in preterm neonates is influenced by gestational age,drug,nutrition,intrauterine growth retardation,birth weight and so on.

关 键 词：早产儿 肾功能 胎龄 药物 出生体质量 窒息 

分 类 号：R722[医药卫生—儿科]