自发性脑脊液鼻漏8例临床分析  

Diagnosis and treatment of spontaneous cerebrospinal fluid rhinorrhea (report of 8 cases)

作　　者：王作伟[1] 王长春[1] 袁庆国[1] 沙成[1] 王大明[1] 

机构地区：[1]卫生部北京医院神经外科,北京100730

出　　处：《中国临床神经外科杂志》2013年第3期135-137,共3页Chinese Journal of Clinical Neurosurgery

摘　　要：目的 研究自发性脑脊液鼻漏诊断和治疗的方法。方法 回顾性分析8例自发性脑脊液鼻漏病例的临床资料,包括患者的临床表现、体重指数、腰穿压力、影像学检查、手术方式以及随访的结果。结果 1例患者经过保守治疗后痊愈。7例患者接受了手术治疗,其中有2例患者接受了2次手术,5例1次性手术成功。8例患者术后随访6月-15年,均无复发。结论 手术结合综合治疗自发性脑脊液鼻漏可取得较满意疗效,准确的术前定位、合适的手术方式以及术后对颅内压的控制是治疗脑脊液鼻漏成功的关键。Objective To investigate the method to diagnose and treat the spontaneous cerebrospinal fluid （CSF） rhinorrhea. Methods The clinical data of 8 patients with spontaneous CSF rhinorrhea, who treated in Beijing Hospital from 1996 to 2012, were analyzed retrospectively, including clinical manifestations, body mass index （BMI）, site of skull base defect, surgical approach, intracranial pressure and therapeutic outcomes. Of 8 patients with spontaneous CSF rhinorrhea, 1 was conservatively treated and 7 were treated by surgery. Results All the patients were cured. Of 7 patients treated by the surgery, 5 underwent an operation and 2 underwent two operations. The following up from 0.5 to 15 years showed that the CSF rhinorrhea did not recurred in all the patients. Conclusions Most patients with spontaneous CSF rhinorrhea need the surgical treatment. They are important to locate the leakage mouth, choose the appropriate repair way and decrease high intracranial pressure to successful surgical treatment in the patients with spontaneous CSF rhinorrhea.

关 键 词：自发性脑脊液鼻漏 手术 修补 颅内压增高 

分 类 号：R765.24[医药卫生—耳鼻咽喉科]