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出 处:《中国现代医生》2013年第4期144-145,共2页China Modern Doctor
摘 要:目的探讨全身预防性应用抗生素对胸部创伤后胸腔闭式引流术后感染的影响。方法随机回顾调查120例胸部创伤后予以胸腔闭式引流术病例,按是否使用抗生素随机分为两组:抗生素组60例预防性应用抗生素头孢硫脒,对照组60例未进行全身预防性应用抗生素;观察并比较两组患者伤口感染和肺炎发病情况、住院日、平均住院费用。结果两组伤口感染率、肺炎发病、住院时间比较差异无统计学意义(P>0.05)。与抗生素组比较,对照组住院费用降低,患者满意度明显升高。结论全身预防性应用抗生素对胸部创伤后胸腔闭式引流术后感染无明显影响。胸部创伤治疗不必常规全身预防性应用抗生素,应严格掌握抗生素的使用指征。Objective To investigate effects of prophylactic antibiotics on preventing infection following tube thoracostomy for chest trauma. Methods A prospective trial was performed on 120 patients received tube thoracostomies for chest trauma. Patients were randomly divided into two groups according to whether the use of antibiotics. 60 patients received cefathiamidine and 60 received no antibiotics. The incidence of trauma infection and pneumonia, duration of hospital stay, and expense were compared between two groups. Results There were no significant difference between two groups in the incidence of trauma infection, pneumonia, and duration of hospital stay (P 〉 0.05). The expense of the control group was significant lower, but the satisfaction higher in comparison to the antibiotic treated group. Conclusion The use of prophylactic antibiotics does not appear to reduce the risk of infection following tube thoracostomy for chest trauma. The conventional systemic prophylactic antibiotics are not necessary for chest trauma and should be strictly controlled.
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