复方鱼腥草口服液质控项目的研究  

Quality control of composite Yuxingcao oral liquid

作　　者：杨伟峰[1] 滕彦[2] 

机构地区：[1]浙江省药品检验所,杭州310004 [2]浙江大学附属第二医院,杭州310009

出　　处：《中国现代应用药学》2000年第5期385-387,共3页Chinese Journal of Modern Applied Pharmacy

摘　　要：目的 :建立复方鱼腥草口服液质量控制项目。方法 :用聚酰胺薄层色谱法对口服液中的主要成分之一绿原酸进行定性鉴别 ;用RP HPLC法对黄芩苷进行含量测定 ,采用ODS柱 ,流动相为甲醇 0 .2 %磷酸水溶液 ( 52∶4 8)。结果 :线性范围 0 .1 62 4～ 1 .62 4 μg ,平均回收率为 1 0 1 .6% ,RSD =1 .2 %。 结论 :上述方法简便、重复性好。可用于本品的质量控制。OBJECTIVE:To establsh a quality control method for composite Yuxingcao oral liquid.METHODD:The main ingredient chlorogenic was identified by polyacrylamide thin layer chromatography and the baicalin was determined by RP HPLC with a ODS column.The mobile phase was methanol 0.2% phosphoric acid water solution(52∶48).RESULTS:The method was linear within the range from 16 to 162μg/ml,the average recovery was 101.6%(RSD 1.2%).CONCLUSION:Both methods were simple and reliable with good repeatability.It may be used for the quality control of this oral liquid.

关 键 词：绿原酸 复方鱼腥草口服液 质量控制项目 PR-HPLC 

分 类 号：R286.0[医药卫生—中药学]