Improved Synthesis and Structure of 3-Carboxy-2-pyrazinecarbohydroxamic Acid  

作　　者：周玮 於孝牛 高艳如 蔡琥 

机构地区：[1]Department of Chemistry,Nanchang University

出　　处：《Chinese Journal of Structural Chemistry》2013年第3期403-407,共5页结构化学（英文）

基　　金：supported by the National Natural Science Foundation of China (No. 20861007);Science Foundation of State Key Laboratory of Structural Chemistry (No. 20100009);Science and Technology Research Projects in Department of Education of Jiangxi Province (No. GJJ08026)

摘　　要：3-Carboxy-2-pyrazinehydroxamic acid was prepared by a one pot reaction starting from pyrazine-2,3-dicarboxylic anhydride with a high yield, and characterized by IR, Mass spectrum, 1H NMR and 13C NMR spectra and single-crystal X-ray diffraction. It crystallizes in triclinic, space group Pī with a=4.8659（10）, b=7.4233（15）, c=11.602（2）, α=96.904（2）, β=92.422（3）, γ=107.454（2）°, V=395.51（14）3 , Z=2, Dc=1.689g/cm3 , F（000）=208, μ（MoKα）=0.149 mm-1 , the final R=0.0473 and wR=0.1306 for 2853 observed reflections （I〉2σ （I））. A three-dimensional framework was assembled through intermolecular hydrogen bonding between water and 3-carboxy-2-pyrazine-carbohydroxamic acid molecules.3-Carboxy-2-pyrazinehydroxamic acid was prepared by a one pot reaction starting from pyrazine-2,3-dicarboxylic anhydride with a high yield, and characterized by IR, Mass spectrum, 1H NMR and 13C NMR spectra and single-crystal X-ray diffraction. It crystallizes in triclinic, space group Pī with a=4.8659（10）, b=7.4233（15）, c=11.602（2）, α=96.904（2）, β=92.422（3）, γ=107.454（2）°, V=395.51（14）3 , Z=2, Dc=1.689g/cm3 , F（000）=208, μ（MoKα）=0.149 mm-1 , the final R=0.0473 and wR=0.1306 for 2853 observed reflections （I〉2σ （I））. A three-dimensional framework was assembled through intermolecular hydrogen bonding between water and 3-carboxy-2-pyrazine-carbohydroxamic acid molecules.

关 键 词：3-carboxy-2-pyrazinecarbohydroxamic acid pyrazine-2 3-dicarboxylic anhydride crystal structure 

分 类 号：O621.3[理学—有机化学]