小儿厌食症动物模型的再研究  

Study on model of juvenile rat with anorexia

作　　者：杜永平[1] 张月萍[1] 汪受传[2] 史健[1] 汪静[1] 吴少华[1] 

机构地区：[1]第四军医大学西京医院中医科,西安710032 [2]南京中医药大学儿科疾病实验室

出　　处：《山西医科大学学报》2000年第5期401-402,共2页Journal of Shanxi Medical University

基　　金：国家自然科学基金!资助课题 (396 70 896 )

摘　　要：采用放免检测和免疫组化方法观察了特制饲料喂养造成的厌食动物模型中枢和外周 β -内啡肽含量变化。结果显示 :模型组动物下丘脑 β-内啡肽合成显著减少 ,外周 β-内啡肽浓度明显下降。提示 β -内啡肽在中枢和外周的含量减少与动物摄食量长期低下有关 ,可能在小儿厌食症发病过程中有一定意义。Endorphin concentration in central and peripheral parts of rat models with anorexia induced by feeding special forage was examined by radioimmunoassay and immunohistochemistry. Results showed the β-Endorphin concentration decreased both hypothalamus and peripheral parts of the model ( P <0 05),suggesting β-Endorphin may play an important role in children anorexia. [WT5”HZ]

关 键 词：厌食症 疾病模型 儿童 内啡肽 放射免疫测定 

分 类 号：R725.735[医药卫生—儿科] R363.13[医药卫生—临床医学]