丙型肝炎患者血清Ig及CH_(50)检测分析  

Serum Ig and CH_(50) in patients with hepatitis C

作　　者：王根维[1] 

机构地区：[1]山西医科大学微生物学与免疫学教研室,太原030001

出　　处：《山西医科大学学报》2000年第5期403-404,共2页Journal of Shanxi Medical University

摘　　要：对 15例急性丙型肝炎和慢性丙型肝炎患者血清Ig及CH50 进行测定。急性期患者血清IgG高于对照组 ,IgM与对照组比较无显著差异 ;IgA低于对照组。慢性期患者血清IgG和IgM均高于对照组 ,IgA与对照组比较无显著差异。总补体活性CH50 在急性与慢性期均低于对照组。结果显示 :丙型肝炎的发病及病情与血清Ig及CH50 有关。除了细胞免疫参与丙肝的发病机制外 ,患者的体液免疫功能也发生改变。这种改变可辅助临床对病情的估价及预后的判断。Serum Ig and CH 50 in patients with chronic( n= 15) and acute( n=15 ) hepatitis c were detected.In acute hepatitis C patients,serum IgG was higher,IgM was similar and IgA was lower compared with control group.In chronic hepatitis C patients,serum IgG and IgM were higher,and IgA was similar compared with control group.CH 50 in the acute and chronic patients was all lower than in control.These data showed that the serum Ig and CH 50 were related to the pathogenesis of hepatitis C.It is suggested that humoral immunity relates to hepatitis C beside cell mediated immunity.The results may provide the supports for clinical estimation of the severity and prognosis of hepatitis C.

关 键 词：丙型肝炎 免疫球蛋白 补体 CH50 发病机制 

分 类 号：R512.63[医药卫生—内科学]