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作 者:李欲航[1] 石蕊[1] 徐晨[1] 江岷[1] 胡亮钉[1] 陈虎[1]
机构地区:[1]中国人民解放军军事医学科学院附属医院全军造血干细胞移植中心,北京100071
出 处:《临床血液学杂志》2013年第2期208-209,共2页Journal of Clinical Hematology
摘 要:患者,女,39岁,诊断"急性淋巴细胞白血病,伴Ph1染色体阳性"。经1疗程诱导缓解方案并同时使用甲磺酸伊马替尼治疗后骨髓达完全缓解,后进行2疗程巩固强化治疗。患者与胞妹HLA配型为5/6相合,2008年12月进行同胞供者外周血造血干细胞移植。A patient with AML plus Ph1+ was performed allogeneic hematopoietic stem cell transplantation(HSCT) after chemotherapies.The donor and receptor were both CMV(+).The patient was completely reconstituted after transplantation.Nineteen months post-transplantation,her urine contained a lot of erythrocytes,but bacteria culture was negative.Other examinations were CMV-pp65(-),CMV-IgG(+),and CMV-IgM(-).She was diagnosed as hemorrhagic cystitis after cystoscope and immunohistochemistry examinations.Ten days after stopping administration of immunosuppressors,the bleeding was terminated.To those HSCT patients with late phase of hemorrhagic cystitis,we need pay more attentions on the diagnosis and treatment of viruses,especially CMV.To those patients who were administered immunosuppressors,the surveillance of CMV infections should be prolonged.
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