环氧基固定化酶载体的研究进展  

Research Progress Of Carriers With Epoxy Groups In Enzymes Immobilization

作　　者：刘文涛[1] 段洪东[1] 王兴建[1] 张娟[1] 张玉森[1] 卜娟[1] 

机构地区：[1]山东轻工业学院化学与制药工程学院,山东济南250353

出　　处：《山东轻工业学院学报（自然科学版）》2012年第3期40-44,共5页Journal of Shandong Polytechnic University

基　　金：山东省自然科学基金(ZR2011BM011)

摘　　要：本文介绍了近几年来环氧基固定化酶载体的研究进展,包括大孔环氧基载体、非大孔环氧基载体及环氧基磁性载体。大孔环氧基载体中的环氧基含量和载体的比表面积、孔结构是影响酶固定化效果的关键因素,比表面积和孔结构主要由致孔剂和交联剂决定。非大孔载体在对酶的固定过程中位阻影响较小,但是它的比表面积相对较小,而且对酶的保护能力比大孔载体差,所以使用性能较差。磁性载体展现出极好的分离和使用性能,是未来研究的重点。This article describes the research progress of carriers with epoxy groups in enzymes immobilization in recent years, including macroporous carriers with epoxy groups, non-macroporous carriers with epoxy groups and magnetic carriers with epoxy groups. The epoxy group content, pore structure and surface area of the macroporous carriers are key factors in determining enzyme immoblization,while cross-linking agent and porogens dominate the surface area and pore structure. Non- macroporous carrier has less resistance in enzyme immobilization, but it has less surface area and the protection of enzyme is weak, so its performance is poor. Magnetic carriers show excellent performance in separation and will be the key direction in future study.

关 键 词：环氧基 大孔吸附载体 非大孔吸附载体 磁性载体 酶固定 

分 类 号：O632.52[理学—高分子化学]