Design,synthesis and preliminary biological evaluation of brain targeting L-ascorbic acid prodrugs of ibuprofen  

作　　者：Xue-Ying Wu Xiao-Cen Li Jie Mi Jing You Li Hai 

机构地区：[1]College of Pharmacy,Chengdu University of Traditional Chinese Medicine [2]Key Laboratory of Drug Targeting and Drug Delivery System of the Education Ministry,Department of Medicinal Chemistry,West China School of Pharmacy,Sichuan University

出　　处：《Chinese Chemical Letters》2013年第2期117-119,共3页中国化学快报（英文版）

基　　金：supported by the Ph.D.Programs Foundation of Ministry of Education of China(No.20110181130011);the National Natural Science Foundation of China(No.81072532)

摘　　要：Received 4 November 2012 Received in revised form 17 December 2012 Accepted 31 December 2012 Available online 4 February 2013Received 4 November 2012 Received in revised form 17 December 2012 Accepted 31 December 2012 Available online 4 February 2013

关 键 词：Vitamin CBrain targetProdrugGLUT1 transporterSVCT2 transporterIbuprofen 

分 类 号：TQ463[化学工程—制药化工]