持续腰大池引流术在中枢神经系统感染疾病中的应用  

Clinical Investigation on the Continuous Lumbar Cerebrospinal Fluid Drainage Applied to the Patients with Central Nervous System Infections

作　　者：赖春颜[1] 梁敏锋[1] 王向槐[1] 龙辉[1] 

机构地区：[1]广东省佛山市第一人民医院,广东佛山528000

出　　处：《热带医学杂志》2013年第2期230-231,共2页Journal of Tropical Medicine

摘　　要：目的观察持续腰大池引流术在治疗中枢神经系统感染疾病中的应用效果。方法对12例接受持续腰大池引流术治疗的中枢神经系统感染疾病患者进行回顾性分析。结果成人平均每日脑脊液引流液量为(298±105)ml,儿童平均每日脑脊液引流液量为(176±93)ml,成人平均持续引流天数为(20±6)d,儿童平均持续引流天数为(20±14)d。应用持续腰大池引流治疗后患者的脑脊液WBC、RBC计数及蛋白定量呈下降趋势,脑脊液生化的葡萄糖、氯化物呈上升趋势;此外持续腰大池引流可降低中枢神经系统感染患者的颅内高压,减少甘露醇的应用剂量。结论在中枢神经系统感染治疗中应用持续腰大池引流术是安全、有效的。Objective This study aims to evaluate the efficacy of continuous lumbar cerebrospinal fluid drainage as a potential therapy applied to the patients with central nervous system infections. Method We retrospectively analyzed the clinical characteristics of patients with central nervous system infections who received the continuous lumbar cerebrospinal fluid drainage. Results The mean volume of drained cerebrospinal fluid in adult and children was （298~ 105 ） ml/day and （176＋93） ml/day, respectively. The mean time of drainage in adults was （20＋6） days, and （20~ 14） days in children.After receiving continuous lumbar cerebrospinal fluid drainage, the number of WBC and RBC in the cerebrospinal fluid and the amount of total proteins were decreased.The situation of intracranial hypertension was improved and the amount of mannitol applied to the patients was also reduced. Conclusion Continuous lumbar cerebrospinal fluid drainage is an effective and safe therapy for patients with central nervous system infections.

关 键 词：中枢神经系统感染 腰大池引流 颅内高压 脑脊液 

分 类 号：R651[医药卫生—外科学]