韶关市2003-2011年流行性乙型脑炎流行特征及抗体检测情况分析  

Analysis on the Serological and Epidemic Characteristics of Japanese B Encephalitis in Shaoguan City from 2003 to 2011

作　　者：宾羽琳[1] 陈艳[2] 徐亮[2] 

机构地区：[1]韶关学院医学院,广东韶关512026 [2]韶关市疾病预防控制中心,广东韶关512026

出　　处：《热带医学杂志》2013年第2期249-250,258,共3页Journal of Tropical Medicine

摘　　要：目的分析韶关市2003-2011年间流行性乙型脑炎(JE)的动态变化趋势及流行特征,为今后防控流行性乙型脑炎提供科学依据。方法采用描述流行病学方法,分析韶关市2003-2011年间乙脑的流行病学特征;对各医院疑似病毒性脑炎病人的血清或脑脊液标本,应用ELISA法进行JEV-IgM抗体检测,进行早期快速诊断。结果韶关市流行性乙脑的流行以男性为主,年龄主要集中在10岁以下儿童,1～5岁最多,流行季节6、7月份为高峰期,10月有一个小起伏。对158例疑似病例血清或脑脊液标本进行JEV-IgM抗体检测,阳性共37例,阳性率为23.0%。结论采用免疫学方法进行检测,应考虑试剂的敏感性和特异性,以提高阳性率;韶关市流行性乙型脑炎的流行在流行时间上具有本地区的特点,防控部门应该对国家计划免疫常规接种计划作出相应的调整,以及制定科学的防控措施。Objective To analyze the epidemic characteristics of Japanese B encephalitis（JE） in Shaoguan from 2003 to 2011 and to provide evidence for the prevention and control of JE. Methods Descriptive epidemiological method was adopted to analyze the epidemiologic features of JE between 2003 and 2011.Serum or cerebrospinal fluid of the suspected viral encephalitis patients was collected and analyzed for JEV-IgM by the ELISA method. Results Most of the infected patients were the male subjects with an age of 1 to 5 years old.The peak period of the epidemic was between June and July,and a minor peak was in October. 37 out of 138 patients（23%）were found to be positive for JEV-IgM. Conclusion A typical seasonal occurrence of epidemic encephalitis B in Shaoguan city was observed.Therefore, the relevant disease control and prevention units are obliged to follow the national immunization plan.

关 键 词：流行性乙型脑炎 流行特征 抗体检测 

分 类 号：R512.32[医药卫生—内科学]