新生儿高胆红素血症320例临床分析  

Clinical analysis of 320 cases of neonatal hyperbilirubinemia

作　　者：韩桂珍[1] 王秀芳[2] 罗忠媛 金梅英[1] 潘晓会[1] 

机构地区：[1]吉林油田总医院儿科,吉林松原138006 [2]吉林油田总医院静点室,吉林松原138006

出　　处：《中国医药科学》2013年第4期151-153,共3页China Medicine And Pharmacy

摘　　要：目的探讨新生儿高胆红素血症病因及临床特点。方法对320例新生儿高胆红素血症病因及临床特点进行详细分析。结果儿科新生儿高胆红素血症发病原因依次为:感染因素(31.87%);围产因素(28.12%);母乳性黄疸(27.18%);新生儿溶血病(9.37%);其他因素(2.50%)及原因不明(0.93%)。感染因素占发病的首位。新生儿溶血病出现黄疸时间明显早于其他组(P<0.05),但重度黄疸所占比例与感染组及母乳性黄疸组比较差异无统计学意义(P>0.05)。母乳性黄疸晚发型所占比例较大,出现黄疸及胆红素达峰值时间均晚于其他组(P<0.05)。所有病例均治愈,无胆红素脑病发生。结论新生儿溶血病多数在生后24h内出现黄疸,在所有黄疸疾病中最早,与其他各组相比差异有统计学意义。母乳性黄疸大多在出生1周后出现黄疸,黄疸持续时间较长,与其他各组相比差异有统计学意义。感染组因疾病不同黄疸出现时间不定,但住院天数相对其他组最长。其他因素及原因不明组高胆红素降至正常值时间最短,与其他各组相比差异有统计学意义。胆红素值各组之间无统计学意义。Objective To investigate the etiology and clinical features of neonatal hyperbilirubinemia. Methods 320 cases of neonatal hyperbilirubinemia in the etiology and clinical features were analyzed in detail. Results The statistics show that,my courtyard department of pediatrics neonatal hyperbilirubinemia causes were infection factors （31.87%）;perinatal factor（28.12%）;breast milk jaundice （27.18%）;the hemolytic disease of the newborn （9.37%）,other factors （2.50%）and unknown cause（0.93%）. Infection factors account for the onset of the first. Hemolytic disease of the newborn jaundice much earlier than in other groups （P 〈 0.05）, but the proportion of severe jaundice and infection group and breast milk jaundice was no significant difference between them （P 〉 0.05）. Breast milk jaundice late onset of larger proportion,the appearance of jaundice and bilirubin peak time were later than in other groups （P 〈 0.05）. All cases were cured,no bilirubin encephalopathy. Conclusion Through the clinical observation,neonatal hemolytic disease most appear icteric within 24 hours after birth,in all jaundice diseases,there are significant differences. Breast milk jaundice mostly appear icteric in one week after birth,jaundice continues for a long time. Because of the different disease, jaundice time are indefinite in infection group,but hospitalization days compared with other groups are the longest. Other factors and reason unknown groups have the shortest time when high bilirubin drop turn to normal. Bilirubin value between each group have no significant difference.

关 键 词：新生儿 高胆红素血症 

分 类 号：R722[医药卫生—儿科]