丙泊酚在高血压性脑出血患者术后的应用  

Effect of propofol in patients with hypertensive cerebral hemorrhage after the application experience

作　　者：王家珍[1] 邹健金 刘光勇[1] 蒋莉[1] 

机构地区：[1]四川省三台县人民医院重症医学科,四川三台621100

出　　处：《中国医药科学》2013年第4期168-169,共2页China Medicine And Pharmacy

摘　　要：目的探讨丙泊酚在高血压性脑出血患者术后的作用。方法将150例高血压性脑出血术后患者分为丙泊酚组和咪唑安定组,除镇静药物不同外其余治疗方法均相同,观察二者的镇静效果及再出血风险和癫痫的发生率。结果 2组在降低再出血及癫痫的发生率方面比较,差异有统计学意义(P<0.05);在镇静效果方面二者差异无统计学意义(P>0.05)。结论丙泊酚在降低再出血风险及癫痫的发生率方面优于咪唑安定,但二者在镇静效果方面没有差异。Objective To explore the effect of propofol in patients with hypertensive cerebral hemorrhage postoperative sedation. Methods 150 hypertensive cerebral hemorrhage sufferers were randomly divided into propofol group and midazolam group.Two groups effect in conscious-sedation and rehaemorrhagia risk and epilepsy incidence were observed. Results Propofol group was significantly lower in rehaemorrhagia risk and epilepsy incidence than midazolam group（P 〈 0.05）,there were no statistical significant difference between propofol group and midazolam group in conscious-sedation effectiveness（P 〉 0.05）. Conclusion Propofol could cut down rehaemorrhagia risk and epilepsy incidence surpass to midazolam.But two group have the same conscious-sedation effectiveness.

关 键 词：丙泊酚 镇静 高血压性脑出血 

分 类 号：R614[医药卫生—麻醉学]