芪胶升白胶囊治疗化疗后白细胞减少的临床疗效观察  

Clinical efficacy of the treatment of Qijiao Shengbai capsules on leukopenia after chemotherapy

作　　者：刘凌[1] 李丹[2] 庞缨[1] 冯莹[1] 

机构地区：[1]广州医学院第二附属医院血液科,广东广州510260 [2]广州医学院第二附属医院肿瘤科,广东广州510260

出　　处：《中国医药科学》2013年第6期15-17,共3页China Medicine And Pharmacy

摘　　要：目的研究芪胶升白胶囊治疗恶性肿瘤化疗后白细胞减少的临床疗效。方法选取2009年1月～2011年12月本院血液科和肿瘤科收治的80例恶性肿瘤患者,按病种分为试验组40例和对照组40例。两组患者均采用常规抗肿瘤方法治疗,试验组患者化疗结束后口服芪胶升白胶囊,对照组化疗后口服利血生片,并予化疗后对患者进行多次血常规检查,比较两组患者白细胞数减少情况及感染发生率。结果两组患者经过化疗后,白细胞数值均有下降,试验组白细胞数低于1.5×109/L的发生率明显低于对照组(P<0.05),白细胞减少的程度明显低于对照组(P<0.05),白细胞恢复至正常所需时间明显缩短(P<0.05),感染发生率明显低于对照组(P<0.05)。结论芪胶升白胶囊治疗恶性肿瘤化疗后白细胞减少取得了满意的临床疗效,减少了感染的发生率,提高了患者的生活质量。Objective To study the clinical efficacy of Qijiaoo Shenghai capsules on leukopenia caused by malignant tumors after chemotherapy. Methods 80 cases of patients with malignant tumors were selected during January 2009 to December 2011, which were randomly divided into experimental group （n=40） and control group （n=40）. All patients were treated by conventional antitumor method. Patients in experimental group were treated by oral Qiijao Shenghai capsules after chemotherapy and patients in control group were treated by oral leucogen after chemotherapy. Patients were checked by repeatedly blood routine examination and compared the white blood cell count and incidence of infection between the two groups. Results The incidence of white blood cell count less than 1.5 × 10^9/L of experimental group was significantly lower than those of the control group（P 〈 0.05）,the leucocyte decrease of experimental group was significantly lower than those of the control grnup（P 〈 0.05）,the time of white blood cells return to normal was significantly shortened（P 〈 0.05）. The incidence of infection was significantly lower than that of the control group （P 〈 0.05）. Conclusion Qijiao Shenghai capsules is effective on leucopenia that after chemotherapy.

关 键 词：芪胶升白胶囊 恶性肿瘤 化疗 白细胞减少 

分 类 号：R273[医药卫生—中西医结合] R730.5[医药卫生—中医肿瘤科]