老年高血压患者心率变异与颈动脉内膜增厚的相关性分析  

Relationship between heart rate variability and carotid intima media thickness in senile hypertension

作　　者：孙焕文[1] 张颖[2] 张向阳[2] 王红[2] 张爱伦[2] 

机构地区：[1]新疆医科大学第一附属医院心功能科,新疆乌鲁木齐830054 [2]新疆医科大学第一附属医院干部病房,新疆乌鲁木齐830054

出　　处：《中国现代医学杂志》2013年第1期66-70,共5页China Journal of Modern Medicine

摘　　要：目的探讨老年高血压病患者心率变异(HRV)与颈动脉内膜厚度(IMT)的关系及其临床意义。方法老年高血压病患者根据IMT分成3组,A组(51例,IMT<1.0 mm),B组(46例,1 mm≤IMT<1.3 mm),C组(48例,IMT≥1.3 mm),检测血脂及其他代谢指标含量,以颈部多普勒超声测定其颈动脉内中膜厚度(IMT),以动态心电图(DCG)检测心律失常及心率变异性。结果 3组患者的室性心律失常和传导阻滞检出率之间的差异均有显著性(P<0.05),3组患者HRV指数(SDNN、SDNN5、PNN50、RMSSD)的差异均有显著性(P<0.05),随着颈动脉病变的进展,3组HRV指数进一步的下降,而且HRV指数与IMT呈负相关。结论老年高血压病颈动脉粥样硬化与HRV有显著相关性。[ Objective ] To investigate the relationship between heart rate variability （HRV） and the carotid in- tima media thickness in senile hypertension. [Methods] One hundred and forty-five senile hypertension patients were categorized into groups by carotid intima media thickness （IMT）： group A （51 cases, IMT〈I.0 mm）, group B （46 cases, 1.0 mm〈IMT〈1.3 mm）, group C （48 cases, IMT≥ 1.3 mm）, HRV was performed using Holter monitoring to e- valuate the cardiac autonomic regulation. [Results ] SDNN, SDNNS, PNNS0, RMSSD in senile hypertension pa- tients were different （P 〈0.05）. With increased carotid intima media thickness, HRV was even lower. HRV was nega- tively related with the severity of carotid intima media thickness. [ Conclusion ] In senile hypertension, HRV is more significantly associated with carotid atherosclerosis.

关 键 词：老年 高血压病 颈动脉硬化 心率变异性 

分 类 号：R544.1[医药卫生—心血管疾病]