代谢综合征伴心功能损害的研究及干预  

Research and intervention in metabolic syndrome combined with cardiac function damage

作　　者：丁帅[1,2] 马军[1] 杨文英[2] 王凤林[2] 李宏亮[2] 

机构地区：[1]开封市疾病预防控制中心,475004 [2]卫生部中日友好医院内分泌科,北京100029

出　　处：《国际内分泌代谢杂志》2013年第2期132-134,共3页International Journal of Endocrinology and Metabolism

摘　　要：代谢综合征是由肥胖、高血压、脂代谢紊乱、高血糖、胰岛素抵抗等组成的临床症候群，这些因素单独或合并存在时均可引起和加重心脏损害。研究显示，代谢综合征的总体危险性可能超过其各组分危险性的简单相加。肥胖、高血压、脂代谢紊乱、高血糖、胰岛素抵抗等通过多种机制引起心肌结构及功能的改变，其治疗应遵循综合干预和个体化原则。Metabolic syndrome is a clinical syndrome,which includes obesity, hypertension, dyslipidemia,hyperglycemia, and insulin resistance. These components cause and aggravate the cardiac damages when exists alone or in combination. Studies showed that the overall risk of metabolic syndrome was more than the simple sum of the risk of its components. Obesity, hypertension, dyslipidemia, hyperglycemia and insulin resistance involved in the change of myocardial structure and function through several mechanisms, the treatment should follow the principle of comprehensive and individual intervention.

关 键 词：代谢综合征 心脏功能 胰岛素抵抗 

分 类 号：R589[医药卫生—内分泌]