甲醛对小鼠精子毒作用实验  

Experiment on the Effect of Formaldehyde on the Sperm Toxicity of Mice

作　　者：易建华[1] 张敬华[1] 高宇香 

机构地区：[1]西安医科大学公共卫生学院,陕西西安710061

出　　处：《工业卫生与职业病》2000年第5期263-264,共2页Industrial Health and Occupational Diseases

摘　　要：用不同剂量 (4,10 ,30mg/kg)甲醛经腹腔注射染毒Icr小鼠连续 5天 ,35天后以颈椎脱臼处死 ,对小鼠精子数量变化、精子活动度改变、精子形态改变进行分析。结果显示 30 ,10mg/kg剂量组精子数量明显少于阴性对照组 ,4,10 ,30mg/kg剂量组精子活动度和精子畸形率与阴性对照组比较有显著性差异。The epididymides were collected 35 days after a successive 5 days i\^p.administration of formaldehyde (4,10,30 mg/kg).The quantity,activity and morphology of sperm were investigated.The results showed that the sperm quantity decreased obviously in the experimented mice at the dose of 10 and 30 mg/kg ,and the sperm activity and sperm deformation ratio of the experimented mice at the dose of 4,10,and 30 mg/kg changed significantly compared with those of the control.This experiment revealed that formaldehyde might have sperm toxicity in mice.

关 键 词：甲醛 小鼠 精子毒作用 实验研究 

分 类 号：R114[医药卫生—卫生毒理学] R996[医药卫生—公共卫生与预防医学]