清热散瘟口服液治疗小儿手足口病  

Therapeutic Effects of Qingre Sanwen Oral Liquid on Children with Hand,Foot and Mouth Disease

作　　者：钟雪梅[1] 张艳玲[1] 郑崇光[1] 刘月皎[1] 李华荣[1] 代纪娟[1] 康闽[1] 许瑛杰[1] 

机构地区：[1]首都儿科研究所感染消化科,北京100020

出　　处：《中国实验方剂学杂志》2013年第7期345-347,共3页Chinese Journal of Experimental Traditional Medical Formulae

摘　　要：目的:观察清热散瘟口服液治疗小儿手足口病的临床疗效。方法:选择门诊94例手足口病患儿随机分成两组,治疗组48例口服清热散瘟口服液(5～10 mL,tid),对照组46例口服利巴韦林颗粒(10～15 mg.kg-1.d-1,tid),疗程3 d。结果:治疗组失访1例,对照组失访2例。两组疗效比较,治疗组显效率(63.83%)、总有效率(93.64%)与对照组(分别为56.81%,86.36%)比较差异无统计学意义。治疗组无1例出现不良反应,对照组有4例患儿出现腹泻,3例患儿出现恶心、呕吐。结论:清热散瘟口服液治疗手足口病疗效好,未见明显不良反应。Objective： To evaluate the therapeutic effects of Qingre Sanwen oral liquid on children with hand, foot and mouth disease （HFMD）. Method： Ninety-four patients with HFMD in our out-patient department were randomly divided into two groups. Forty-eight patients were treated with Qingre Sanwen oral liquid （5-10 mL, tid）, forty-six patients were treated with ribavirin （10-15 mg·kg-1·d-1 ）. The treatment lasted for 3 days. Result： The marked effect rates were 63.82% and 56. 81% in the observation group and in the controls accordingly without significant difference. The total effect rates were 93.64% and 86.36% in the observation group and in the controls respectively without significant difference. The observation group showed no adverse reaction. The control group had diarrhea in four cases and vomiting in 3 cases. Conclusion： Qingre Sanwen oral liquid has a good therapeutic effect on children with HFMD, and no adverse reactions.

关 键 词：手足口病 清热散瘟口服液 儿童 

分 类 号：R287[医药卫生—中药学]